Abstract |
The purpose of the study was to assess the effectiveness and safety of long-term application of fenspiride, an anti-inflammatory drug, in patients with chronic obstructive pulmonary disease ( COPD) under outpatient conditions. The drug was studied on 24 COPD patients. Fenspiride application resulted in improvement in bronchoobstructive syndrome and external respiration parameters, as well as a significant increase in exercise tolerance. In patients with stable stage I COPD, the use of fenspiride as a part of therapeutic regimen leads to better clinical results than in stage II patients. Long-term application of fenspiride in medium therapeutic doses under outpatient conditions is associated with positive clinical effects and leads to significant improvement in quality of life.
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Authors | S I Butorov, V I Muntianu |
Journal | Klinicheskaia meditsina
(Klin Med (Mosk))
Vol. 85
Issue 5
Pg. 43-7
( 2007)
ISSN: 0023-2149 [Print] Russia (Federation) |
PMID | 17665604
(Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anti-Inflammatory Agents
- Bronchodilator Agents
- Spiro Compounds
- fenspiride
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Topics |
- Adult
- Aged
- Ambulatory Care
- Anti-Inflammatory Agents
(therapeutic use)
- Bronchodilator Agents
(therapeutic use)
- Female
- Humans
- Male
- Middle Aged
- Pulmonary Disease, Chronic Obstructive
(drug therapy, physiopathology)
- Quality of Life
- Severity of Illness Index
- Spiro Compounds
(therapeutic use)
- Treatment Outcome
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