Studies of Johne's Disease in Canada: XI. Complement-Fixation Titres and Blood Cell Picture.

Abstract

Complement-fixation titres and haemograms were determined monthly during a period of approximately one year for nine cattle with Johne's disease. Three of four experimentally infected animals died during the interval or shortly afterwards; all three developed high complement-fixing titres with Johne's bacillus antigen. The experimentally infected animal that survived was serologically reactive for a few months, then became negative. One of the naturally infected cows exhibited a relatively high complement-fixing titre throughout but the other four were serologically negative or occasionally weekly reactive. All nine cattle showed a variable degree of neutrophilia and lymphopaenia but an absolute eosinopaenia was observed only in the three that died.

• Authors: C E Rice, H Konst, J Carrière
• Journal: Canadian journal of comparative medicine and veterinary science (Can J Comp Med Vet Sci) Vol. 28 Issue 10 Pg. 248-52 (Oct 1964) ISSN: 0316-5957 [Print] Canada
• PMID: 17649535 (Publication Type: Journal Article)