NaFeEDTA fortified soy sauce showed higher iron absorption rate in Chinese females.

Abstract

OBJECTIVE:

NaFeEDTA was considered as a promising iron fortificant for controlling iron deficiency anemia. Soy sauce is a suitable food carrier for iron fortification and is a popular condiment in China. Iron absorption rates of NaFeEDTA and FeSO4 were observed and compared in adult female subjects.

METHODS:

The stable isotope tracer method was used in Chinese females consuming a typical Chinese diet. Ten healthy young Chinese women were selected as subjects in the 15-day study. A plant-based diet was used based on the dietary pattern of adult women in the 1992 National Nutrition Survey. Six milligram of 54Fe in 54FeSO4 soy sauce and 3 mg 58Fe in Na58FeEDTA soy sauce were given to the same subjects in two days. Food samples and fecal samples were collected and analyzed.

RESULTS:

Iron absorption rates of NaFeEDTA and FeSO4 were 10.51% +/- 2.83 and 4.73% +/- 2.15 respectively. The 58Fe (NaFeEDTA) absorption was significantly higher than that of 54Fe (FeSO4) (P < 0.01). The iron absorption rate from NaFeEDTA was 1.2 times higher than that from FeSO4 in Chinese adult women consuming a typical Chinese diet.

CONCLUSION:

The higher absorption rate of NaFeEDTA suggested that NaFeEDTA would be a better iron fortificant used in soy sauce for the controlling of iron deficiency anemia in China.

• Authors: Jun-Sheng Huo, Xiao-Guang Yang, Jian-Hua Piao, Jun-Quan Gao, Hong Miao, Bo Yu, Cheng-Qian Lu, Jun-Shi Chen
• Journal: Biomedical and environmental sciences : BES (Biomed Environ Sci) Vol. 20 Issue 2 Pg. 126-30 (Apr 2007) ISSN: 0895-3988 [Print] China
• PMID: 17624186 (Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Ferric Compounds
• Ferrous Compounds
• ferrous sulfate
• Edetic Acid
• Iron
• Fe(III)-EDTA

Topics

• Adolescent
• Adult
• China
• Edetic Acid (pharmacokinetics)
• Female
• Ferric Compounds (pharmacokinetics)
• Ferrous Compounds (pharmacokinetics)
• Food, Fortified
• Humans
• Iron (pharmacokinetics)
• Soy Foods