Abstract | PURPOSE OF REVIEW: A range of impulse control and repetitive behaviors presumed to be related to dopaminergic medications has been recognized in Parkinson's disease. These behaviors are linked by their incentive or reward-based and repetitive natures and overlap with addictions. The behaviors include pathological gambling, hypersexuality, compulsive shopping, and compulsive eating and are related to punding and compulsive medication use. In patients on dopamine agonists, these behaviors as a group are relatively common, can have potentially devastating psychosocial consequences and are commonly hidden. RECENT FINDINGS: Recent studies have investigated prevalence rates and associated factors. The literature on these behaviors in Parkinson's disease, including definitions, epidemiology, pathophysiology and management, is reviewed. The relationship to medications, Parkinson's disease and individual susceptibility is examined. SUMMARY:
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Authors | Valerie Voon, Marc N Potenza, Teri Thomsen |
Journal | Current opinion in neurology
(Curr Opin Neurol)
Vol. 20
Issue 4
Pg. 484-92
(Aug 2007)
ISSN: 1350-7540 [Print] England |
PMID | 17620886
(Publication Type: Journal Article, Review)
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Chemical References |
- Antiparkinson Agents
- Dopamine Agonists
- Receptors, Dopamine
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Topics |
- Antiparkinson Agents
(adverse effects)
- Compulsive Behavior
(chemically induced)
- Disruptive, Impulse Control, and Conduct Disorders
(chemically induced, epidemiology, physiopathology)
- Dopamine Agonists
(adverse effects)
- Humans
- Neuronal Plasticity
(physiology)
- Parkinson Disease
(complications, drug therapy, physiopathology)
- Receptors, Dopamine
(metabolism)
- Reward
- Stereotyped Behavior
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