Abstract | OBJECTIVE: PATIENTS AND METHODS: Details of TURPs done between January 2003 and December 2005 at one institution were obtained from the operating theatre database. Patients were divided by indication (retention/LUTS). Clinical data and histology reports were then reviewed and bivariate and logistic regression used to compare the pathological features between these groups. RESULTS: Of 406 patients, 374 had evaluable data; 70% of men with urinary retention had ACI, vs 45% of those with LUTS (P < 0.001). On logistic regression, the pathological factors associated with TURP for acute retention compared to that for LUTS were ACI, old age, and resection weight to a lesser degree. CONCLUSION:
Inflammation appears to be important in the pathogenesis and progression of BPH. In this study, the risk of urinary retention due to BPH was significantly greater in men with ACI than in those without, and the association of TURP for retention with ACI was stronger than that with prostate weight. This finding might offer new avenues for the medical treatment of men with LUTS due to BPH.
|
Authors | Vibhash C Mishra, Darrell J Allen, Christophoros Nicolaou, Haytham Sharif, Charles Hudd, Omer M A Karim, Hanif G Motiwala, Marc E Laniado |
Journal | BJU international
(BJU Int)
Vol. 100
Issue 2
Pg. 327-31
(Aug 2007)
ISSN: 1464-4096 [Print] England |
PMID | 17617139
(Publication Type: Journal Article)
|
Topics |
- Acute Disease
- Aged
- Aged, 80 and over
- Chronic Disease
- Disease Progression
- Humans
- Male
- Middle Aged
- Prostatic Hyperplasia
(complications, surgery)
- Prostatism
(etiology, surgery)
- Prostatitis
(complications, surgery)
- Regression Analysis
- Retrospective Studies
- Transurethral Resection of Prostate
- Urinary Retention
(etiology, surgery)
|