Abstract | OBJECTIVE: The purpose of this study was to examine agricultural risk factors for chronic bronchitis among nonsmoking farm women. METHODS: We used self-reported enrollment data from the 21,541 nonsmoking women in the Agricultural Health Study to evaluate occupational risk factors for prevalent chronic bronchitis among farm women. Odds ratios ( ORs) for chronic bronchitis for occupational exposures were adjusted for age, state, and related agricultural exposures. RESULTS: Applying manure and driving combines were independently associated with chronic bronchitis. Off-farm job exposures associated with chronic bronchitis were organic dusts, asbestos, gasoline, and solvents. Five pesticides were associated with chronic bronchitis after multivariate adjustment and sensitivity analyses: dichlorvos (OR=1.63, 95% CI=1.01, 2.61), DDT (OR=1.67, 95% CI=1.13, 2.47), cyanazine (OR=1.88, 95% CI=1.00, 3.54), paraquat (OR=1.91, 95% CI=1.02, 3.55), and methyl bromide (OR=1.82, 95% CI=1.02, 3.24). CONCLUSION: Pesticides as well as grain and dust exposures were associated with chronic bronchitis among nonsmoking farm women.
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Authors | Martin Valcin, Paul K Henneberger, Greg J Kullman, David M Umbach, Stephanie J London, Michael C R Alavanja, Dale P Sandler, Jane A Hoppin |
Journal | Journal of occupational and environmental medicine
(J Occup Environ Med)
Vol. 49
Issue 5
Pg. 574-83
(May 2007)
ISSN: 1076-2752 [Print] United States |
PMID | 17495700
(Publication Type: Journal Article, Research Support, N.I.H., Intramural, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Aged
- Agriculture
- Bronchitis, Chronic
(epidemiology, etiology, physiopathology)
- Confidence Intervals
- Female
- Humans
- Iowa
- Middle Aged
- North Carolina
- Occupational Exposure
- Odds Ratio
- Pesticides
(adverse effects)
- Prospective Studies
- Surveys and Questionnaires
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