[Protein C reactive and glaucoma].

Abstract

PURPOSE:

To observe the possible implications of the C reactive protein in pathogenesis of the glaucoma.

METHODS:

A clinical observational prospective study on 2 groups: group A 14 glaucomatous patients and group B--control (12 normal subjects) without history of ocular pathology or general pathology known to be associated with high plasma levels of CRP. The groups were homogeneous about the age and sex distribution. CRP levels were evaluated by tests with high specificity.

RESULTS:

The plasma CRP level reveals important differences (p < 0,0001) on the two groups: 3,87 +/- 0,8 mg/dl in the group A and 0,68 +/- 0,13 mg/dl in the control group.

CONCLUSIONS:

Glaucoma is associated with high plasma levels of CRP. In the complex pathogenesis of glaucoma, in which the vascular factor has his well known place, the inflammatory vascular modifications may represent an important component.

• Authors: C Stefan, A Nenciu, Diana Melinte, Cristina Malcea, Irina Nae, Olga Afanasiuc
• Journal: Oftalmologia (Bucharest, Romania : 1990) (Oftalmologia) Vol. 50 Issue 4 Pg. 82-5 ( 2006) ISSN: 1220-0875 [Print] Romania
• Vernacular Title: Proteina C reactivă si glaucomul.
• PMID: 17345810 (Publication Type: English Abstract, Journal Article)

Chemical References

• C-Reactive Protein

Topics

• Aged
• C-Reactive Protein (metabolism)
• Case-Control Studies
• Enzyme-Linked Immunosorbent Assay
• Female
• Glaucoma (blood)
• Glaucoma, Open-Angle (blood)
• Humans
• Male
• Predictive Value of Tests
• Prospective Studies
• Statistics, Nonparametric