Alcohol injection for the intrauterine treatment of chorioangioma in a pregnancy with transfusion resistant fetal anemia: a case report.

Abstract

Chorioangiomas are usually small, clinically inevident, benign vascular lesions of the placenta, but larger ones may cause serious perinatal and neonatal complications. There is need for in utero intervention in these fetuses. Several interventions are described to relieve pathophysiologic insult on fetus. Alcohol injection is one of the therapeutic interventions. In this case, we present a patient with chorioangioma and early onset of hydrops fetalis and polyhydramnios at 24th week of gestation. Successful intratumoral injection of absolute ethyl alcohol relieved hydrops fetalis and polyhydramnios. Unfortunately, pregnancy ended at 28th week and a 1,330 g fetus was delivered.

• Authors: Ozgur Deren, Ozgur Ozyuncu, Lutfu S Onderoglu, Tekin Durukan
• Journal: Fetal diagnosis and therapy (Fetal Diagn Ther) Vol. 22 Issue 3 Pg. 203-5 ( 2007) ISSN: 1015-3837 [Print] Switzerland
• PMID: 17228160 (Publication Type: Case Reports, Journal Article)
• Copyright: (c) 2007 S. Karger AG, Basel.

Chemical References

• Ethanol

Topics

• Adult
• Anemia (therapy)
• Blood Transfusion, Intrauterine
• Ethanol (administration & dosage, therapeutic use)
• Female
• Fetal Therapies (methods)
• Hemangioma (diagnostic imaging, therapy)
• Humans
• Hydrops Fetalis (diagnostic imaging, drug therapy)
• Infant, Newborn
• Injections, Intralesional
• Placenta Diseases (diagnostic imaging, therapy)
• Polyhydramnios (diagnostic imaging, drug therapy)
• Pregnancy
• Ultrasonography, Prenatal