HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Therapy and course of disease in spontaneous esophageal perforations].

AbstractINTRODUCTION:
Esophageal perforations occur spontaneously or as a complication of endoscopic procedures. Especially in spontaneous perforation there is ongoing debate regarding the best treatment options.
METHODS:
24 patients that were treated at two surgical centers (University Halle, City-hospital Bielefeld) after spontaneous esophageal perforations between 1996 and 2005 were analysed retrospectively.
RESULTS:
All patients but one underwent surgical treatment with in 2 cases additional stent implantation. Average stay in hospital was 53 days. In-hospital-lethality was 25% (overall lethality 37.5%). Concerning the therapeutic outcome there was no link between patients' age, localization or size of the perforation and the time interval between perforation and treatment. In 22 patients diagnosis was made > 12hrs after the event.
CONCLUSIONS:
Main problem of the Boerhaave-syndrome is the septic-toxic disease. Prognostic criteria are the patients' health-state and not factors like size of perforation, time of delay or localization of the perforation. Since in case of survival esophageal resection shows good long-term-results, in doubt a radical surgical procedure should be recommended as primary option. Implanting an esophageal stent might become a useful mean of treating patients with spontaneous perforations.
AuthorsF Thermann, M Thermann, H Dralle
JournalZentralblatt fur Chirurgie (Zentralbl Chir) Vol. 131 Issue 6 Pg. 454-9 (Dec 2006) ISSN: 0044-409X [Print] Germany
Vernacular TitleChirurgische Therapie und Verlauf nach spontaner Osophagusruptur.
PMID17206563 (Publication Type: English Abstract, Journal Article)
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Cause of Death
  • Combined Modality Therapy
  • Empyema, Pleural (diagnosis, mortality, surgery)
  • Esophageal Diseases (diagnosis, mortality, surgery)
  • Esophagoplasty (methods)
  • Female
  • Humans
  • Length of Stay (statistics & numerical data)
  • Male
  • Mallory-Weiss Syndrome (diagnosis, mortality, surgery)
  • Mediastinitis (diagnosis, mortality, surgery)
  • Middle Aged
  • Postoperative Complications (mortality)
  • Prognosis
  • Retrospective Studies
  • Rupture, Spontaneous (diagnosis, mortality, surgery)
  • Shock, Septic (mortality)
  • Stents
  • Survival Rate
  • Tomography, X-Ray Computed
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: