Osteo-odonto-keratoprosthesis: a human model of autotransplant.

Abstract

We evaluated the microscopical changes that occurred when bone and dental tissue were exposed to such a foreign environment as the ocular surface and anterior chamber in 17 osteo-odonto-keratoprostheses removed from the recipient's eye after 1 to 20 years. Histochemical methods were performed to demonstrate elastic and precursor fibers, while immunohistochemical procedures were used to study the distribution of collagen types I to VI. Islands of heterotopic, newly formed bone were observed in the dentin and the periodontal space, leading to focal dentoalveolar ankylosis. Remodelling and disappearance of the periodontal ligament was never diffuse.

• Authors: Irene Pecorella, Maurizio Taloni, Antonio Ciardi, Robert A Alexander, Giancarlo Falcinelli
• Journal: Current eye research (Curr Eye Res) Vol. 31 Issue 10 Pg. 835-43 (Oct 2006) ISSN: 0271-3683 [Print] England
• PMID: 17050275 (Publication Type: Journal Article)

Chemical References

• Collagen

Topics

• Adolescent
• Adult
• Aged
• Alveolar Process (metabolism, pathology, transplantation)
• Bone Remodeling
• Child
• Collagen (metabolism)
• Corneal Diseases (surgery)
• Device Removal
• Extracellular Matrix
• Female
• Humans
• Male
• Middle Aged
• Models, Biological
• Prostheses and Implants
• Prosthesis Design
• Tooth Root (metabolism, pathology, transplantation)
• Transplantation, Autologous (pathology)