In the dietary management of
severe acute malnutrition in children, there is evidence to support the WHO Manual's protocol of cautious feeding of a low energy and
protein formula with small frequent feeds in the initial phase of treatment, particularly in
kwashiorkor. However, this initial milk diet (WHO F-75) might benefit from increasing the sulphur
amino acid,
phosphorus and
potassium content and reducing the
lactose content, but further studies are needed. Careful
tube-feeding results in faster initial recovery and
weight gain, but has a significant risk of aspiration in poorly supervised settings. Ready-to-
use therapeutic food is an important recent advance in the dietary management of
malnutrition in ambulatory settings, allowing more effective prevention programmes and earlier discharge from hospital where community follow-up is available. It should be included in future protocols. There is very good evidence on the use of
micronutrients such as
zinc, and preliminary evidence suggests that smaller doses of daily
vitamin A are preferable to a single large dose on admission for severe
malnutrition.