[Transfer factor as specific immunomodulator in the treatment of moderate-severe atopic dermatitis].

Abstract

BACKGROUND:

Atopic dermatitis is a skin inflammatory disease which has been associated to high levels of IgE, eosinophiles and change of T lymphocytes. The transfer factor is an immunomodulator active substance and decreases the number of inflammatory cells and the severity of the symptoms of atopic dermatitis.

OBJECTIVE:

To determine the efficacy of the transfer factor as treatment of moderate and severe atopic dermatitis.

MATERIAL AND METHODS:

Articles related to treatment with transfer factor in the atopic dermatitis were looked up in Medline and EMBASE, and the ones referring to controlled studies in patients with moderate and severe atopic dermatitis in accord to SCORAD.

RESULTS:

We found seven articles with 121 patients and 88 controls demonstrating significant decrease in the symptoms of the SCORAD index, decreased IgE, and eosinophils in patients treated with transfer factor.

CONCLUSIONS:

The transfer factor is a choice treatment for moderate and severe atopic dermatitis.

• Authors: G Flores Sandoval, J Gómez Vera, M Orea Solano, J López Tiro, E Serrano, Abraham Rodríguez, Azucena Rodríguez, S Estrada Parra, N Jiménez Saab
• Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) (Rev Alerg Mex) 2005 Nov-Dec Vol. 52 Issue 6 Pg. 215-20 ISSN: 0002-5151 [Print] Mexico
• Vernacular Title: Factor de transferencia como inmunomodulador específico en el tratamiento de la dermatitis atópica moderada a severa.
• PMID: 16568705 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Transfer Factor

Topics

• Dermatitis, Atopic (drug therapy, immunology)
• Humans
• Severity of Illness Index
• Transfer Factor (therapeutic use)