Radiotherapy for splenomegaly.

Abstract

Radiotherapy for massive, symptomatic splenomegaly has been used in a palliative setting since the early 1990's. Massive splenomegaly may be seen in CML, CLL, hairy cell leukemia and splenic marginal zone lymphomas, prolymphocytic leukemia, myeloproliferative disorders such as polycythaemia rubra, polycythaemia vera or essential thrombocytosis or myelofibrosis. Splenic radiation therapy has been shown to be effective in palliation of the signs and symptoms due to massive splenomegaly. We present here one such case of myelofibrosis where the patient was treated with radiotherapy to the spleen for symptomatic relief. The patient achieved excellent response to the treatment.

• Authors: H Mod, G Prasiko, A K Jha, P P Chaurasia, R Srivastava
• Journal: JNMA; journal of the Nepal Medical Association (JNMA J Nepal Med Assoc) 2005 Jul-Sep Vol. 44 Issue 159 Pg. 97-9 ISSN: 0028-2715 [Print] Nepal
• PMID: 16554863 (Publication Type: Case Reports, Journal Article)

Topics

• Brachytherapy
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Palliative Care
• Primary Myelofibrosis (complications, diagnosis)
• Radiotherapy Dosage
• Risk Assessment
• Severity of Illness Index
• Splenomegaly (etiology, physiopathology, radiotherapy)
• Treatment Outcome