Abstract | OBJECTIVE: METHOD: Topical 5% povidone-iodine solution was applied onto the ocular surface just prior to transferring the patient into the operative theater for cataract surgery. Other prophylactic measures were allowed to continue as before. Patients developing postoperative intraocular inflammation and undergoing intravitreal antibiotic injection were included as occurrences of endophthalmitis. Alteration in endophthalmitis rate was analyzed using a 'p control chart' of a statistical process control method. The incidence in the povidone-iodine-receiving group was compared to those before implementation and concurrent nonreceiving groups. RESULT: The postoperative endophthalmitis rate showed a significant reduction after introduction of povidone-iodine. A year before, 9 of 3,052 eyes developed endophthalmitis (0.294%). After introduction, this occurred in 4 of 4,089 eyes receiving povidone-iodine (0.097%) and 1 of 502 nonreceiving eyes (0.199%) in the following 16 months. Despite the apparent lower rate, comparison between groups was not statistically significant. Moderate to severe but tolerable eye irritation after application was reported in 6.6%. No other adverse events were detected. CONCLUSION:
|
Authors | Adisak Trinavarat, La-ongsri Atchaneeyasakul, Cherdchai Nopmaneejumruslers, Kantima Inson |
Journal | Dermatology (Basel, Switzerland)
(Dermatology)
Vol. 212 Suppl 1
Pg. 35-40
( 2006)
ISSN: 1018-8665 [Print] Switzerland |
PMID | 16490973
(Publication Type: Journal Article)
|
Chemical References |
- Anti-Infective Agents, Local
- Povidone-Iodine
|
Topics |
- Administration, Topical
- Adult
- Aged
- Aged, 80 and over
- Anti-Infective Agents, Local
(administration & dosage)
- Cataract Extraction
(adverse effects)
- Child, Preschool
- Endophthalmitis
(epidemiology, etiology, prevention & control)
- Female
- Humans
- Incidence
- Male
- Middle Aged
- Povidone-Iodine
(administration & dosage)
- Preoperative Care
- Treatment Outcome
|