Abstract | PURPOSE: SUBJECTS AND METHODS: RESULTS: In 1997-1998, 17% of the cohort were regular aspirin users. Aspirin use increased with coronary heart disease risk from 13% in persons with a 10-year risk less than 6% (low risk) to 23% in those with a 10-year risk greater than 20% (highest risk) (P for trend < .001). Blacks were less likely to use aspirin (13%) than whites (20%). In multivariate analysis, black race was still associated with lower aspirin use (odds ratio 0.66, 95% confidence interval 0.49-0.89). In 1997-1998 and 2002 to 2003, aspirin use increased from 17% to 32% among those still free of coronary heart disease (P < .001), and the association with coronary heart disease risk continued (P for trend < .001). Despite their high coronary heart disease risk, diabetic persons were not more likely to use aspirin than nondiabetic persons, even in 2002 and 2003 (odds ratio 0.89, 95% confidence interval 0.56-1.40). CONCLUSION: Regular use of aspirin by older adults with no history of cardiovascular disease has increased in recent years. Individuals at higher coronary heart disease risk are more likely to take aspirin, but there is room for considerable improvement in targeting those at high risk, particularly diabetic persons and blacks.
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Authors | Nicolas Rodondi, Eric Vittinghoff, Jacques Cornuz, Javed Butler, Jingzhong Ding, Suzanne Satterfield, Anne B Newman, Tamara B Harris, Stephen B Hulley, Douglas C Bauer, Health, Aging, and Body Composition Study research group |
Journal | The American journal of medicine
(Am J Med)
Vol. 118
Issue 11
Pg. 1288
(Nov 2005)
ISSN: 1555-7162 [Electronic] United States |
PMID | 16271917
(Publication Type: Journal Article, Multicenter Study, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
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Topics |
- Aged
- Aged, 80 and over
- Aspirin
(therapeutic use)
- Cohort Studies
- Coronary Disease
(epidemiology, prevention & control)
- Diabetes Complications
(epidemiology, prevention & control)
- Drug Utilization
(statistics & numerical data)
- Ethnicity
(statistics & numerical data)
- Female
- Follow-Up Studies
- Humans
- Male
- Motor Activity
- Patient Acceptance of Health Care
(statistics & numerical data)
- Pennsylvania
(epidemiology)
- Prospective Studies
- Risk
- Socioeconomic Factors
- Tennessee
(epidemiology)
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