Abstract | BACKGROUND: MATERIALS AND METHODS: RESULTS:
Integrin alpha(v)beta3 was expressed in MDA-MB-231 and MDA-MB-435, but not in MKL-4 or T-47D, using both immunohistochemistry and flow cytometry. By RT-PCR, positive bands for both alpha(v) and beta3 subunits were identified in MDA-MB-231 and 435, while only the alpha(v) subunit mRNA was present in MKL-4 and T-47D. BM was common in vivo following inoculation with MDA-MB-231 or 435, but not with MKL-4. CONCLUSION:
|
Authors | Shin Takayama, Seiichiro Ishii, Tadashi Ikeda, Shigeru Masamura, Masakazu Doi, Masaki Kitajima |
Journal | Anticancer research
(Anticancer Res)
2005 Jan-Feb
Vol. 25
Issue 1A
Pg. 79-83
ISSN: 0250-7005 [Print] Greece |
PMID | 15816522
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Animals
- Bone Neoplasms
(metabolism, secondary)
- Breast Neoplasms
(metabolism, pathology)
- Cell Line, Tumor
- Humans
- Immunohistochemistry
- Integrin alphaVbeta3
(biosynthesis)
- Neoplasm Transplantation
- Rats
- Rats, Nude
- Transplantation, Heterologous
|