A comparison of anesthetic quality in propofol-spinal anesthesia and propofol-fentanyl anesthesia for total knee arthroplasty in elderly patients.

Abstract

STUDY OBJECTIVE:

To compare propofol plus spinal anesthesia during spontaneous ventilation using the Laryngeal Mask Airway and propofol plus fentanyl anesthesia during mechanical ventilation with an endotracheal tube on quality of recovery after anesthesia.

DESIGN:

Prospective, randomized study.

SETTING:

Hirosaki National Hospital.

PATIENTS:

150 patients (aged > 70 years) undergoing total knee arthroplasty.

INTERVENTIONS:

Patients were divided randomly into two groups, to receive spontaneous ventilation with a Laryngeal Mask Airway during propofol-spinal anesthesia, or to receive propofol-fentanyl anesthesia with mechanical ventilation via endotracheal tube.

MEASUREMENTS:

Quality of anesthesia recovery such as nausea, vomiting, headache, pain throat, hoarse voice, back pain, dizziness, feeling comfortable, dreaming, recovery times in recovery of anesthesia, recovery times, postoperative pain, confusion, was assessed.

MAIN RESULTS:

The frequency of postoperative pain throat, hoarse voice, and nausea was significantly lower in the propofol-spinal anesthesia group than the propofol-fentanyl anesthesia group. The time to extubation, emergence, response to commands, and orientation were significantly faster (p < 0.001) in the propofol-spinal anesthesia group than the propofol-fentanyl anesthesia group. The frequency of postoperative confusion occurring in the propofol-spinal anesthesia group during the first 24 hours was significantly lower than that of the propofol-fentanyl anesthesia group (p = 0.03).

CONCLUSIONS:

Propofol-spinal anesthesia provided better and faster recovery than did propofol-fentanyl anesthesia for elderly patients undergoing total knee arthroplasty.

• Authors: Akira Kudoh, Hajime Takase, Tomoko Takazawa
• Journal: Journal of clinical anesthesia (J Clin Anesth) Vol. 16 Issue 6 Pg. 405-10 (Sep 2004) ISSN: 0952-8180 [Print] United States
• PMID: 15567642 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Anesthetics, Combined
• Anesthetics, Intravenous
• Fentanyl
• Propofol

Topics

• Aged
• Anesthesia Recovery Period
• Anesthesia, Spinal
• Anesthetics, Combined (administration & dosage, adverse effects)
• Anesthetics, Intravenous (administration & dosage, adverse effects)
• Arthroplasty, Replacement, Knee
• Female
• Fentanyl (administration & dosage, adverse effects)
• Humans
• Intubation, Intratracheal (methods)
• Male
• Propofol (administration & dosage, adverse effects)
• Respiration, Artificial