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Natural medicine: the genus Angelica.

Abstract
More than 60 species of medicinal plants belong to the genus Angelica (Family: Apiaceae). Many of these species have long been used in ancient traditional medicine systems, especially in the far-east. Various herbal preparations containing Angelica species are available over-the-counter, not only in the far-eastern countries, but also in the western countries like USA, UK, Germany, etc. For centuries, many species of this genus, e.g. A. acutiloba, A. archangelica, A. atropupurea, A. dahurica, A. japonica, A. glauca, A. gigas, A. koreana, A. sinensis, A. sylvestris, etc., have been used traditionally as anti-inflammatory, diuretic, expectorant and diaphoretic, and remedy for colds, flu, influenza, hepatitis, arthritis, indigestion, coughs, chronic bronchitis, pleurisy, typhoid, headaches, wind, fever, colic, travel sickness, rheumatism, bacterial and fungal infections and diseases of the urinary organs. Active principles isolated from these plants mainly include various types of coumarins, acetylenic compounds, chalcones, sesquiterpenes and polysaccharides. This review evaluates the importance of the genus Angelica in relation to its traditional medicinal uses, alternative medicinal uses in the modern society and potential for drug development, and summarises results of various scientific studies on Angelica species or Angelica-containing preparations for their bioactivities including, antimicrobial, anticancer, antitumour, analgesic, anti-inflammatory, hepatoprotective, nephroprotective, etc.
AuthorsS D Sarker, L Nahar
JournalCurrent medicinal chemistry (Curr Med Chem) Vol. 11 Issue 11 Pg. 1479-500 (Jun 2004) ISSN: 0929-8673 [Print] United Arab Emirates
PMID15180579 (Publication Type: Evaluation Study, Journal Article)
Chemical References
  • Biological Factors
Topics
  • Angelica (chemistry, classification)
  • Biological Factors (isolation & purification, pharmacology, therapeutic use)
  • Complementary Therapies (methods, trends)
  • Humans
  • Medicine, Traditional
  • Phytotherapy (trends)
  • Plants, Medicinal (chemistry, classification)

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