Abstract | BACKGROUND: Sphincter of Oddi manometry is helpful in selecting patients with sphincter of Oddi dysfunction who will respond to sphincterotomy. However, studies have shown that sphincter of Oddi manometry is associated with a high risk of post-procedure pancreatitis. The primary objective of this study was to evaluate the safety of sphincter of Oddi manometry in patients with sphincter of 2Oddi dysfunction. The secondary objective was to determine the risk factors for post-ERCP pancreatitis in patients with sphincter of Oddi dysfunction. METHODS: Data were collected retrospectively for 268 patients who had elective ERCP performed at 3 tertiary care medical centers between 1996 and 2000. Consecutive patients with suspected sphincter of Oddi dysfunction formed the case group; the control group consisted of patients with bile duct stone. The case group was further subclassified into group A, patients who underwent sphincter of Oddi manometry followed by immediate ERCP, and group B, patients who had ERCP without manometry. The rate of post-ERCP acute pancreatitis was compared between case and control groups. RESULTS: CONCLUSIONS:
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Authors | Pankaj Singh, Suryakanth R Gurudu, Samuel Davidoff, Michael V Sivak Jr, Anant Indaram, Franklin E Kasmin, Valerie Nozdak, Richard C k Wong, Gerard Isenberg, Bernard Stark, Simmy Bank, Amitabh Chak |
Journal | Gastrointestinal endoscopy
(Gastrointest Endosc)
Vol. 59
Issue 4
Pg. 499-505
(Apr 2004)
ISSN: 0016-5107 [Print] United States |
PMID | 15044885
(Publication Type: Journal Article)
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Topics |
- Acute Disease
- Adult
- Aged
- Cholangiopancreatography, Endoscopic Retrograde
(adverse effects)
- Female
- Humans
- Logistic Models
- Male
- Manometry
(adverse effects)
- Middle Aged
- Pancreatitis
(etiology)
- Retrospective Studies
- Risk Factors
- Sphincter of Oddi
- Stents
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