[Study on endotoxin levels of acute and chronic periapical periodontitis].

Abstract

OBJECTIVE:

To compare the endotoxin levels between acute and chronic periapical periodontitis with different clinical symptoms.

METHODS:

10 cases of acute periapical priodontitis(Group 1), 10 cases of chronic periapical periodontitis (group 2, the diameter of apical radiolucency area was less than 2 mm), 10 cases of chronic periapical periodontitis with sinus(group 3, the diameter of apical radiolucency area was greater than 2 mm), 10 cases of chronic periapical periodontitis without sinus (group 4, the diameter of apical radiolucency area was greater than 2 mm), were included in the study. Chromogenic substrate method of limulus amebocyte lysate(LAL) test was used to measure the endotoxin level.

RESULTS:

Endotoxin concentrations in group 2 were significantly lower than those in group 1, group 3 and group 4(P < 0.01).

CONCLUSION:

Endotoxin plays a very important role in the initiation and development of periapical periodotitis and is closely associated with clinical symptoms and apical radiolucency degree.

• Authors: Tao Hu, Hong Tan, Yu-dong Xu
• Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology (Hua Xi Kou Qiang Yi Xue Za Zhi) Vol. 22 Issue 1 Pg. 52-3 (Feb 2004) ISSN: 1000-1182 [Print] China
• PMID: 15017702 (Publication Type: English Abstract, Journal Article)

Chemical References

• Endotoxins
• Root Canal Irrigants

Topics

• Acute Disease
• Bacteria
• Chronic Disease
• Endotoxins (analysis)
• Humans
• Limulus Test
• Periapical Periodontitis (metabolism, microbiology)
• Root Canal Irrigants