Abstract | OBJECTIVE: METHODS: Male Wistar rats, subjected to bilateral renal ischemia for 45 min followed by reperfusion for up to 48 h, were administered 15-deoxy-Delta(12,14)-prostaglandin J2 (1 mg/kg, intravenously) 5 min prior to and again after 3 or 12 h reperfusion. RESULTS: CONCLUSIONS:
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Authors | Prabal Kumar Chatterjee, Nimesh S A Patel, Salvatore Cuzzocrea, Paul A J Brown, Keith N Stewart, Helder Mota-Filipe, Domenico Britti, Wolfgang Eberhardt, Josef Pfeilschifter, Christoph Thiemermann |
Journal | Cardiovascular research
(Cardiovasc Res)
Vol. 61
Issue 3
Pg. 630-43
(Feb 15 2004)
ISSN: 0008-6363 [Print] England |
PMID | 14962493
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- 15-deoxy-delta(12,14)-prostaglandin J2
- Calcium-Binding Proteins
- I-kappa B Proteins
- Lipopolysaccharides
- Membrane Glycoproteins
- NF-kappa B
- Nerve Tissue Proteins
- Synaptotagmin I
- Intercellular Adhesion Molecule-1
- Synaptotagmins
- Nitric Oxide
- Interferon-gamma
- Nitric Oxide Synthase
- Nitric Oxide Synthase Type II
- Nos2 protein, rat
- Prostaglandin D2
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Topics |
- Animals
- Calcium-Binding Proteins
- Cells, Cultured
- I-kappa B Proteins
(analysis)
- Intercellular Adhesion Molecule-1
(analysis)
- Interferon-gamma
(pharmacology)
- Ischemia
(metabolism, prevention & control)
- Kidney
(chemistry, metabolism)
- Kidney Diseases
(metabolism, prevention & control)
- Kidney Tubules
(drug effects)
- Lipopolysaccharides
(pharmacology)
- Male
- Membrane Glycoproteins
(analysis)
- Models, Animal
- NF-kappa B
(metabolism)
- Nerve Tissue Proteins
(analysis)
- Nitric Oxide
(analysis)
- Nitric Oxide Synthase
(analysis)
- Nitric Oxide Synthase Type II
- Prostaglandin D2
(analogs & derivatives, pharmacology, therapeutic use)
- Rats
- Rats, Wistar
- Reperfusion Injury
(metabolism, prevention & control)
- Synaptotagmin I
- Synaptotagmins
- Time Factors
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