Effects of Unkei-to on FSH, LH and estradiol in anovulatory young women with hyper- or hypo-functioning conditions.

Abstract

Eight weeks treatment with Unkei-to induced a significant increase in plasma follicle stimulating hormone (FSH), luteinizing hormone (LH) and estradiol levels in hyper- (robust) and hypo- (asthenia) functioning patients with first- and second-grade amenorrhea. We observed no significant differences in the rate of change of these hormones between hyper- and hypo-functioning patients. Ovulation occurred in 61.3% and 66.7% of patients with first-grade amenorrhea, and in 27.3% and 22.4% of patients with second-grade amenorrhea, respectively. No significant difference was observed in the ovulation rate after an 8-week treatment with Unkei-to between hyper- and hypo-functioning patients. These results indicate that Unkei-to is effective in improving gonadotropin and estradiol secretion in the treatment of either hyper- or hypo-functioning anovulatory women.

• Authors: Takahisa Ushiroyama, Toshimitsu Hosotani, Yoshiki Yamashita, Hidetoshi Yamashita, Minoru Ueki
• Journal: The American journal of Chinese medicine (Am J Chin Med) Vol. 31 Issue 5 Pg. 763-71 ( 2003) ISSN: 0192-415X [Print] Singapore
• PMID: 14696679 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)

Chemical References

• Drugs, Chinese Herbal
• Gonadotropins
• unkei-to
• Luteinizing Hormone
• Follicle Stimulating Hormone

Topics

• Adolescent
• Adult
• Amenorrhea (drug therapy)
• Drugs, Chinese Herbal (therapeutic use)
• Female
• Follicle Stimulating Hormone (metabolism)
• Gonadotropins (metabolism)
• Humans
• Luteinizing Hormone (drug effects, metabolism)
• Male
• Ovulation (drug effects)
• Pituitary Gland (drug effects, metabolism)
• Time Factors
• Treatment Outcome