Spectinomycin-resistant Neisseria gonorrhoeae.

Abstract

Neisseria gonorrhoeae resistant to high levels of spectinomycin (more than 2,048 microng/ml), were isolated from specimens obtained from a patient with urethritis. The bacterial resistance to spectinomycin is probably due to ribosomal changes that are a result of a chromosomal mutation. If spectinomycin fails to cure gonorrhea, spectinomycin resistance should be considered.

• Authors: C Thornsberry, H Jaffee, S T Brown, T Edwards, J W Biddle, S E Thompson
• Journal: JAMA (JAMA) Vol. 237 Issue 22 Pg. 2405-6 (May 30 1977) ISSN: 0098-7484 [Print] United States
• PMID: 140251 (Publication Type: Case Reports, Journal Article)

Chemical References

• Spectinomycin

Topics

• Adult
• Drug Resistance, Microbial
• Georgia
• Gonorrhea (drug therapy)
• Humans
• Male
• Microbial Sensitivity Tests (methods)
• Neisseria gonorrhoeae (drug effects)
• Spectinomycin (pharmacology, therapeutic use)