Abstract | OBJECTIVE: STUDY DESIGN: A randomized controlled trial recruited 32 infants between 24 and 32 weeks. Immediately before delivery, mothers were randomized to ICC (cord clamped at 5 to 10 seconds) or DCC (30- to 45-second delay in cord clamping) groups. RESULTS: Intention-to-treat analyses revealed that the DCC group were more likely to have higher initial mean blood pressures (adjusted OR 3.4) and less likely to be discharged on oxygen (adjusted OR 8.6). DCC group infants had higher initial glucose levels (ICC=36 mg/dl, DCC=73.1 mg/dl; p=0.02). CONCLUSION: The research design is feasible. The immediate benefit of improved blood pressure was confirmed and other findings deserve consideration for further study.
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Authors | Judith S Mercer, Margaret M McGrath, Angelita Hensman, Helayne Silver, William Oh |
Journal | Journal of perinatology : official journal of the California Perinatal Association
(J Perinatol)
Vol. 23
Issue 6
Pg. 466-72
(Sep 2003)
ISSN: 0743-8346 [Print] United States |
PMID | 13679933
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Topics |
- Blood Pressure
- Clinical Protocols
- Constriction
- Feasibility Studies
- Female
- Hematocrit
- Humans
- Infant, Newborn
- Infant, Premature
- Pilot Projects
- Pregnancy
- Pregnancy Outcome
- Prospective Studies
- Research Design
- Time Factors
- Umbilical Cord
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