[Autoantibodies to the thyroid gland in hemoblastoses and cytopenias].

Abstract

AIM:

To study the level of thyroid antibodies (TAB) in blood diseases.

MATERIAL AND METHODS:

TAB levels dynamics was studied in 413 patients with hematological diseases.

RESULTS:

Increased incidence of cases with high Ab titer to thyroid microsomal antigen was found. High and moderate titers were revealed in 33% of all examinees, including 41%, 22%, 32% and 29% among patients with immune cytopenia, chronic lymphoid leukemia, generalized mature-cell lymphoma and myeloproliferative diseases, respectively. These high and moderate titers were rather stable. In 15% patients Ab were elevated insignificantly, this rise being unstable.

CONCLUSION:

Stable high titers of antibodies to thyroid antigens point to increased incidence rates of concomitant autoimmune hyroiditis in patients with blood diseases.

• Authors: A P Shinkarkina, Iu E Vinogradova, D L Vinogradov, A M Poverennyĭ
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 75 Issue 2 Pg. 62-5 ( 2003) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Autoantitela k shchitovidnoĭ zheleze pri gemoblastozakh i tsitopeniiakh.
• PMID: 12685396 (Publication Type: English Abstract, Journal Article)

Chemical References

• Autoantibodies

Topics

• Autoantibodies (blood)
• Female
• Hematologic Diseases (immunology)
• Humans
• Male
• Thyroid Gland (immunology)