Cimetidine therapy for epidermodysplasia verruciformis.

Abstract

A 16-year-old boy with an 8-year history of multiple slightly keratotic papules on his face, trunk, and limbs, is described. On the basis of clinical features, histologic examination of 2 lesions and positivity for HPV 5, a diagnosis of epidermodysplasia verruciformis was made. Treatment with oral cimetidine (40 mg/kg per day) induced a marked improvement after 3 months of therapy, with no relapse at a 6-month follow-up.

• Authors: Giuseppe Micali, Maria Rita Nasca, Federica Dall'Oglio, Maria Letizia Musumeci
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 48 Issue 2 Suppl Pg. S9-10 (Feb 2003) ISSN: 0190-9622 [Print] United States
• PMID: 12582373 (Publication Type: Case Reports, Journal Article)

Chemical References

• Histamine H2 Antagonists
• Cimetidine

Topics

• Adolescent
• Cimetidine (therapeutic use)
• Epidermodysplasia Verruciformis (drug therapy, pathology)
• Histamine H2 Antagonists (therapeutic use)
• Humans
• Male
• Treatment Outcome