[Evaluation of the effect of streptomycin perfusion of the labyrinth in the treatment of Meniere's disease and endolymphatic hydrops].

Abstract

OBJECTIVE:

To investigate the clinical effect of streptomycin perfusion of the labyrinth (SPL) in the treatment of Meniere's disease.

METHOD:

13 patients with Meniere's disease and 3 patients with delayed endolymphatic hydrops (DEH) underwent SPL. The follow-up time was between 5 and 7 years (average 6.3 years).

RESULT:

Vertigo was completely controlled in 9 patients, substantialy controlled in 4, limitedly controlled in 2 and not controlled in 1. Hearing was improved in 1 patients, stabilized in 5 and worse in 10. Tinnitus was improved in 3 patients, stabilized in 5 and worse in 8.

CONCLUSION:

SPL is a safe and effective method in the treatment of Meniere's disease and DEH, but the hearing may be insulted and tinnitus may be worse in some patients.

• Authors: A Q Peng, Y D Lu, J H Ren, Z Chen
• Journal: Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology (Lin Chuang Er Bi Yan Hou Ke Za Zhi) Vol. 14 Issue 10 Pg. 438-9 (Oct 2000) China
• PMID: 12563709 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Streptomycin

Topics

• Adult
• Anti-Bacterial Agents (administration & dosage)
• Chemotherapy, Cancer, Regional Perfusion
• Ear, Inner
• Endolymphatic Hydrops (drug therapy)
• Female
• Follow-Up Studies
• Humans
• Male
• Meniere Disease (drug therapy)
• Middle Aged
• Streptomycin (administration & dosage)