Abstract | OBJECTIVE: It has been suggested that there is a decrease in the collagen content of the fetal membranes when there is premature rupture of the membranes before the onset of labor. This study was designed to determine whether decreased amniochorion collagen production (as measured by reduced amounts of messenger RNA) or alterations in relative production of different fibrillar and nonfibrillar collagens are associated with premature rupture of the membranes. STUDY DESIGN: RESULTS: CONCLUSION:
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Authors | Natalie B Meirowitz, John C Smulian, Rita A Hahn, Peihong Zhou, Susan Shen-Schwarz, George H Lambert, Donald R Gerecke, Marion K Gordon |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 187
Issue 6
Pg. 1679-85
(Dec 2002)
ISSN: 0002-9378 [Print] United States |
PMID | 12501083
(Publication Type: Journal Article)
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Chemical References |
- COL14A1 protein, human
- Collagen Type I
- Collagen Type III
- Collagen Type V
- Collagen Type XII
- Fibril-Associated Collagens
- Glycoproteins
- RNA, Messenger
- Collagen
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Topics |
- Amnion
(chemistry)
- Chorion
(chemistry)
- Collagen
(genetics, metabolism)
- Collagen Type I
(genetics)
- Collagen Type III
(genetics)
- Collagen Type V
(genetics)
- Collagen Type XII
(analysis, genetics)
- Female
- Fetal Membranes, Premature Rupture
(metabolism)
- Fibril-Associated Collagens
(genetics)
- Fluorescent Antibody Technique
- Gene Expression
- Gestational Age
- Glycoproteins
(genetics, metabolism)
- Humans
- Immunohistochemistry
- Pregnancy
- RNA, Messenger
(analysis)
- Reverse Transcriptase Polymerase Chain Reaction
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