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Terpenes from Juniperus przewalskii and their antitumor activities.

Abstract
Two new diterpenes were isolated from Juniperus przewalskii, together with 17 known terpense. Their structures were elucidated by spectroscopic methods (IR, MS, 1H, 13C and 2DNMR). In addition, 3 alpha-hinokiol (3) and 3 alpha-hydroxymannol (9) exhibited effective antitumor activities to cervical carcinoma (HeLa) and human ovarian carcinoma (HO-8910) cell lines.
AuthorsWen-Shu Wang, Er-Wei Li, Zhong-Jian Jia
JournalDie Pharmazie (Pharmazie) Vol. 57 Issue 5 Pg. 343-5 (May 2002) ISSN: 0031-7144 [Print] Germany
PMID12061261 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antineoplastic Agents, Phytogenic
  • Terpenes
Topics
  • Antineoplastic Agents, Phytogenic (isolation & purification, pharmacology)
  • China
  • Female
  • HeLa Cells
  • Humans
  • Juniperus (chemistry)
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Optical Rotation
  • Ovarian Neoplasms (drug therapy)
  • Spectrophotometry, Infrared
  • Terpenes (isolation & purification, pharmacology)
  • Tumor Cells, Cultured

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