Corticosteroid injection vs. nonsteroidal antiinflammatory drug and splinting in carpal tunnel syndrome.

Abstract

OBJECTIVE:

To compare the efficacy of local corticosteroid injection to a nonsteroidal antiinflammatory drug and splinting for the treatment of carpal tunnel syndrome.

DESIGN:

This study was a prospective, unblinded, randomized clinical trial with an 8-wk follow-up. Thirty-three hands of 23 patients were randomly treated with acemetacine and splinting (group A) or with corticosteroid injection (group B). Clinical (symptom severity scale, visual analog scale, Tinel and Phalen tests) and electromyographic evaluations were performed on initial visit and after 8 wk.

RESULTS:

Clinical and electromyographic parameters, which were similar at baseline, were improved in both groups after treatment. Improvement was also similar when both groups were compared at 8 wk.

CONCLUSION:

Both splinting combined with the use of a nonsteroidal antiinflammatory drug and steroid injection into the carpal tunnel resulted in significant improvement in carpal tunnel syndrome.

• Authors: Reyhan Celiker, Sule Arslan, Fatma Inanici
• Journal: American journal of physical medicine & rehabilitation (Am J Phys Med Rehabil) Vol. 81 Issue 3 Pg. 182-6 (Mar 2002) ISSN: 0894-9115 [Print] United States
• PMID: 11989514 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Inflammatory Agents
• Anti-Inflammatory Agents, Non-Steroidal
• Methylprednisolone Acetate
• acemetacin
• Methylprednisolone
• Indomethacin

Topics

• Adult
• Anti-Inflammatory Agents (administration & dosage, therapeutic use)
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Carpal Tunnel Syndrome (physiopathology, therapy)
• Electromyography
• Female
• Follow-Up Studies
• Humans
• Indomethacin (analogs & derivatives, therapeutic use)
• Injections
• Male
• Methylprednisolone (administration & dosage, analogs & derivatives, therapeutic use)
• Methylprednisolone Acetate
• Middle Aged
• Pain Measurement
• Prospective Studies
• Severity of Illness Index
• Splints