[Subreum efficacy and tolerance in patients with early rheumatic arthritis].

Abstract

AIM:

To evaluate effectiveness and tolerance of subreum in early rheumatoid arthritis (RA).

MATERIAL AND METHODS:

44 patients with early rheumatoid arthritis. Subreum was given as a single drug and in combination with other basic drugs. Tolerance was evaluated in all the examinees, the effect--in 13 patients who finished the 6-month treatment by the articular syndrome, by ACR, DAS and HAQ criteria.

RESULTS:

By DAS, a good response was achieved in 2 patients (15%), a satisfactory one--in 3 (23%) patients. By ACR criteria, a 20% and 50% improvement was obtained in 3 (23%) and 4 (31%) patients. Side effects were absent in 41 (93%) patients.

CONCLUSION:

Subreum proved effective and well tolerable in early RA.

• Authors: O V Stepanets, N V Chichasova, M B Nasonova, E L Nasonov
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 79 Issue 11 Pg. 58-62 ( 2001) ISSN: 0023-2149 [Print] Russia (Federation)
• Vernacular Title: Effektivnost' i perenosimost' subreuma u bol'nykh s rannim revmatoidnym artritom.
• PMID: 11811114 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Antigens, Bacterial
• OM 89

Topics

• Adjuvants, Immunologic (therapeutic use)
• Age Factors
• Antigens, Bacterial (therapeutic use)
• Arthritis, Rheumatoid (drug therapy)
• Drug Tolerance
• Female
• Humans
• Male
• Middle Aged
• Treatment Outcome