Abstract | PURPOSE: METHODS: Clinical examination was performed by slit-lamp biomicroscopy, indirect ophthalmoscopy, color fundus photography, and focal electroretinography. Histopathologic examination of the enucleated left eye consisted of light microscopy. RESULTS: Light microscopy demonstrated a discrete macular lesion characterized by focal absence of photoreceptor cells and retinal pigment epithelium. Bruch's membrane was attenuated in the center of the lesion and associated with marked atrophy of the choriocapillaris. Adjacent to the central lesion, some lipofuscin was identified in the retinal pigment epithelium. CONCLUSIONS:
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Authors | K W Small, I Voo, J Flannery, N Udar, B J Glasgow |
Journal | Transactions of the American Ophthalmological Society
(Trans Am Ophthalmol Soc)
Vol. 99
Pg. 233-7; discussion 237-8
( 2001)
ISSN: 0065-9533 [Print] United States |
PMID | 11797312
(Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Topics |
- Aged
- Bruch Membrane
(pathology)
- Electroretinography
- Female
- Humans
- Macular Degeneration
(genetics, pathology)
- North Carolina
- Pedigree
- Photoreceptor Cells, Vertebrate
(pathology)
- Retinal Ganglion Cells
(pathology)
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