[Efficacy of a single-day administration of levofloxacin for the prevention of urinary tract infections after urogenital examinations and treatments for outpatients].
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| Abstract |
The clinical efficacy of a single-day oral administration of levofloxacin (LVFX) for the prevention of urinary tract infections (UTI) after urogenital examinations and treatments for outpatients was assessed. A single-day oral administration of LVFX, 100 mg three times a day, was compared to a single dose intra-muscular injection of 100 mg netilmicin sulfate or 100 mg dibekacin sulfate. Three of 219 cases (1.4%) and 7 of 304 cases (2.3%) contracted UTI in the single-day oral administration group and the single dose intra-muscular injection group, respectively. Adverse reactions were observed in 3 of 219 cases (1.4%) and 27 of 304 cases (8.8%) in the single-day oral administration group and the single dose intra-muscular injection group, respectively. In the single dose intra-muscular injection group, UTI and adverse reactions were more severe than in the single-day oral administration group. Therefore, a single-day oral administration of LVFX was superior to a single dose intra-muscular injection of netilmicin sulfate or dibekacin sulfate in the prevention of UTI with less probability of the adverse effects. A single-day oral administration of LVFX was concluded to be sufficient for the prevention of UTI caused by examinations and treatments for outpatients.
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| Authors | T Hayashi, Y Sakai, K Saito, G Arai, N Hyochi, M Suzuki, H Masuda, S Kawakami, T Okuno, T Kobayashi, Y Kageyama, K Kihara |
| Journal | Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 47 Issue 11 Pg. 773-5 (Nov 2001) ISSN: 0018-1994 [Print] Japan |
| PMID | 11771168 (Publication Type: English Abstract, Journal Article) |
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