Phenobarbital following phototherapy for Crigler-Najjar syndrome type II with good fetal outcome: a case report.

Abstract

In the presence of severe hyperbilirubinemia in Crigler-Najjar syndrome Type II, a fetus is at risk for kernicterus. A 34-year-old woman, gravida 4, para 1, with Crigler-Najjar syndrome Type II was treated with phenobarbital administration following phototherapy during each of 2 pregnancies. Both infants were healthy and developed normally.

• Authors: T Ito, C Katagiri, S Ikeno, H Takahashi, N Nagata, N Terakawa
• Journal: The journal of obstetrics and gynaecology research (J Obstet Gynaecol Res) Vol. 27 Issue 1 Pg. 33-5 (Feb 2001) ISSN: 1341-8076 [Print] Australia
• PMID: 11330728 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Anticonvulsants
• Phenobarbital

Topics

• Adult
• Anticonvulsants (therapeutic use)
• Crigler-Najjar Syndrome (therapy)
• Female
• Humans
• Infant, Newborn
• Phenobarbital (therapeutic use)
• Phototherapy
• Pregnancy
• Pregnancy Complications (therapy)
• Pregnancy Outcome