One hundred consecutive treatments with holmium: YAG laser for pulmonary bullae: especially in conjunction with gelatin-resorcinol formaldehyde-glutaraldehyde glue adhesion.

Abstract

BACKGROUND AND OBJECTIVE:

We have widely used a Ho:YAG laser to treat bullae thoracoscopically.

STUDY DESIGN/MATERIALS AND METHODS:

Bullae with broad necks were treated with a Ho:YAG laser thoracoscopically. Because one patient relapsed after application of fibrin glue in the early period, a DEXON (polyglycolic acid) mesh patch soaked in fibrin glue was used through a 2-cm opening in the subsequent cases. Lastly, gelatin-resorcinol formaldehyde-glutaraldehyde (GRFG) glue was applied through a 5-mm opening instead of a DEXON mesh after coagulation.

RESULTS:

In the 38 patients patched with DEXON mesh soaked in fibrin glue and 56 patched with GRFG glue after coagulation, none relapsed.

CONCLUSION:

Combined uses of fibrin glue plus DEXON mesh or GRFG glue were effective when bullae were treated with the Ho:YAG laser. However, the wound was smaller and more cosmetic in the GRFG glue group than in the DEXON mesh plus fibrin glue group.

• Authors: S Kaseda, T Aoki, N Hangai, K Shimizu, H Kiguchi
• Journal: Lasers in surgery and medicine (Lasers Surg Med) Vol. 28 Issue 3 Pg. 255-8 ( 2001) ISSN: 0196-8092 [Print] United States
• PMID: 11295761 (Publication Type: Clinical Trial, Comparative Study, Journal Article)
• Copyright: Copyright 2001 Wiley-Liss, Inc.

Chemical References

• Drug Combinations
• Resorcinols
• gelatin-resorcin-formaldehyde-glutaraldehyde adhesive
• Formaldehyde
• Gelatin
• Glutaral
• Holmium

Topics

• Blister (pathology, surgery)
• Combined Modality Therapy
• Drug Combinations
• Equipment Design
• Follow-Up Studies
• Formaldehyde (pharmacology)
• Gelatin (pharmacology)
• Glutaral (pharmacology)
• Holmium
• Humans
• Laser Coagulation (methods)
• Lung Diseases (pathology, surgery)
• Reference Values
• Resorcinols (pharmacology)
• Sensitivity and Specificity
• Surgical Instruments
• Thoracoscopy (methods)
• Treatment Outcome