[A case of HIV encephalopathy with dementia which showed significant improvement after the combination antiretroviral therapy].

Abstract

We report a 63-year-old male with HIV encephalopathy, whose initial symptom was acutely progressing dementia. He tested positive for HIV antibody, and HIV-RNA count was 2.8 x 10(5) copy/ml. All opportunistic infections that could cause dementia were ruled out. Dementia remarkably improved after the combination antiretroviral therapy of three types of drugs, two being nucleoside analog reverse transcriptase inhibitors and one being a protease inhibitor. The combination therapy could be very effective for the treatment of HIV dementia.

• Authors: Y Mizoi, M Takagi, H Hoshino, S Matsuoka, T Adachi
• Journal: Rinsho shinkeigaku = Clinical neurology (Rinsho Shinkeigaku) Vol. 40 Issue 2 Pg. 178-80 (Feb 2000) ISSN: 0009-918X [Print] Japan
• PMID: 10835942 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-HIV Agents
• HIV Protease Inhibitors
• Lamivudine
• Zidovudine
• Indinavir

Topics

• AIDS Dementia Complex (complications, drug therapy, etiology)
• Anti-HIV Agents (therapeutic use)
• Drug Therapy, Combination
• HIV Protease Inhibitors (therapeutic use)
• Humans
• Indinavir (therapeutic use)
• Lamivudine (therapeutic use)
• Male
• Middle Aged
• Treatment Outcome
• Zidovudine (therapeutic use)