Abstract | BACKGROUND: Scleroderma is uncommon in childhood. The aim of our study was to analyze the frequency of different clinical forms, their prognostic significance, biological features, and co-morbidities and to assess the pertinence of therapeutic options. PATIENTS AND METHODS: The files of 70 children with primary scleroderma seen from 1980 to 1997 were retrospectively reviewed. RESULTS: DISCUSSION: Our findings emphasize that scleroderma occurs readily in childhood, unlike what has been reported 10 years ago. Prognosis depends on functional impairment resulting from major sequelae particularly important in localized forms and the life-threatening situations occurring in systemic forms.
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Authors | C Bodemer, M Belon, D Hamel-Teillac, J C Amoric, S Fraitag, A M Prieur, Y De Prost |
Journal | Annales de dermatologie et de venereologie
(Ann Dermatol Venereol)
Vol. 126
Issue 10
Pg. 691-4
(Oct 1999)
ISSN: 0151-9638 [Print] France |
Vernacular Title | Sclérodermies de l'enfant: étude rétrospective de 70 cas. |
PMID | 10604006
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Adrenal Cortex Hormones
- Antibodies, Antinuclear
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Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Age Factors
- Age of Onset
- Antibodies, Antinuclear
(analysis)
- Child
- Comorbidity
- Dermatomyositis
(epidemiology)
- Disease Progression
- Eosinophilia
(epidemiology)
- Fasciitis
(epidemiology)
- Female
- Humans
- Male
- Mixed Connective Tissue Disease
(epidemiology)
- Paris
(epidemiology)
- Prognosis
- Retrospective Studies
- Scleroderma, Localized
(epidemiology)
- Scleroderma, Systemic
(epidemiology)
- Sex Factors
- Time Factors
- Treatment Outcome
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