Abstract | PURPOSE: SETTING: Ophthalmology Department, Minjoz Hospital, Besançon, France. METHODS: Seventy-four patients were randomized to receive either tetracaine 1% or diclofenac 0.1% after undergoing PRK. Tetracaine was instilled at 30 minute intervals for 24 hours. Diclofenac was instilled four times a day for 3 days. All patients were allowed to use oral Diantalvic ( paracetamol- noramidopyrine) as a rescue analgesic if the study medications failed to control the ocular pain. Visual analog pain charts were used to record pain levels every hour for 30 hours after surgery. A subjective questionnaire was to be completed by the patient to evaluate discomfort every day for 3 days. Computer analysis of photography performed at D0, D1, D3, was used to evaluate the rate of epithelial closure. RESULTS: Women had significantly more pain. Patients in the diclofenac group had significantly less pain. No statistically significant difference was seen in the rate of epithelial closure. CONCLUSION:
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Authors | M Montard, C Chopin, B Delbosc, M Muhieddine |
Journal | Journal francais d'ophtalmologie
(J Fr Ophtalmol)
Vol. 22
Issue 1
Pg. 14-20
(Feb 1999)
ISSN: 0181-5512 [Print] France |
Vernacular Title | Tétracaïne versus diclofénac dans le traitement de la douleur après photokératectomie réfractive. |
PMID | 10221185
(Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anesthetics, Local
- Anti-Inflammatory Agents, Non-Steroidal
- Ophthalmic Solutions
- Tetracaine
- Diclofenac
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Topics |
- Adult
- Anesthetics, Local
(administration & dosage, adverse effects)
- Anti-Inflammatory Agents, Non-Steroidal
(administration & dosage, adverse effects)
- Diclofenac
(administration & dosage, adverse effects)
- Female
- Humans
- Lasers, Excimer
- Male
- Ophthalmic Solutions
- Pain Measurement
- Photorefractive Keratectomy
- Tetracaine
(administration & dosage, adverse effects)
- Treatment Outcome
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