Metabolic Side Effects of Drugs and Substances

Specific effects of drugs and substances on metabolic pathways such as those occurring through the CYTOCHROME P-450 ENZYME SYSTEM. These include effects that often result in DRUG INTERACTIONS; FOOD-DRUG INTERACTIONS; and HERB-DRUG INTERACTIONS.

Also Known As:

Drug Effects on Metabolism; Metabolic Side Effects of Drugs; Metabolic Side Effects of Substances; Substance Effects on Metabolism

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Experts

1.	Amisten, Stefan: 2 articles (02/2015 - 09/2013)
2.	Persaud, Shanta J: 2 articles (02/2015 - 09/2013)
3.	Salehi, Albert: 2 articles (02/2015 - 09/2013)
4.	Aichler, Michaela: 1 article (02/2016)
5.	Eickelberg, Oliver: 1 article (02/2016)
6.	Fernandez, Isis E: 1 article (02/2016)
7.	Sun, Na: 1 article (02/2016)
8.	Walch, Axel: 1 article (02/2016)
9.	Wei, Mian: 1 article (02/2016)
10.	Wu, Yin: 1 article (02/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Metabolic Side Effects of Drugs and Substances:

1.	LigandsIBA 02/01/2015 - "This atlas highlights knowledge gaps in the current understanding of adipose tissue GPCR function, and identifies GPCR/ligand/drug interactions that might affect lipolysis, which is important for understanding and predicting metabolic side effects of drugs. " 09/01/2013 - "The islet GPCRome highlights knowledge gaps in the current understanding of islet GPCR function, and identifies GPCR/ligand/drug interactions that might affect insulin secretion, which are important for understanding the metabolic side effects of drugs. "
2.	Arachidonic Acid (Vitamin F)IBA 01/01/1989 - "A method for distinguishing drug effects on metabolism of endogenously released arachidonic acid (AA) and exogenously added AA was developed by the use of washed rat platelets. "
3.	DiureticsIBA 01/01/1990 - "Although the real impact of some of these changes is unproven, it is possible that one or more of the metabolic side effects of drugs such as diuretics and beta-blockers may offset some of the benefits of reduced blood pressure. "
4.	pirfenidoneIBA 02/01/2016 - "The combination of pharmametabolome with histological features provides detailed mapping of drug effects on metabolism as response of healthy lung tissue to pirfenidone treatment."