Mad2 Proteins

Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES.

Also Known As:

Mad2 Mitotic Arrest Deficient-like 1 Proteins

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bian, A P: 1 article (01/2014)
2.	Qin, L: 1 article (01/2014)
3.	Shi, H R: 1 article (01/2014)
4.	Su, K: 1 article (01/2014)
5.	Zhang, Y: 1 article (01/2014)
6.	Zhao, Q: 1 article (01/2014)

Related Diseases

1.	Endometrial Neoplasms (Endometrial Cancer) 01/01/2014 - "Bub1 and Mad2 proteins were negatively correlated in the endometrial carcinoma tissues (r = - 0.719, p < 0.001). "