Tiapride Hydrochloride

A benzamide derivative that is used as a dopamine antagonist.

Also Known As:

Equilium; FLO-1347; Tiapridal; Tiapridex; Tiaprizal; FLO 1347; FLO1347; Hydrochloride, Tiapride; Monohydrochloride, Tiapride; Tiapride; Tiapride Monohydrochloride; N,N-Diethyl-2-((2-methoxy-5-(methylsulfonyl)benzoyl)amino)ethanaminium chloride

Networked: 238 relevant articles (36 outcomes, 46 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Roessner, Veit: 4 articles (03/2022 - 05/2013)
2.	Roos, Raymund A C: 2 articles (04/2022 - 01/2017)
3.	Cavanna, Andrea E: 2 articles (03/2022 - 01/2019)
4.	Münchau, Alexander: 2 articles (03/2022 - 05/2013)
5.	Rothenberger, Aribert: 2 articles (03/2022 - 07/2004)
6.	Stern, Jeremy S: 2 articles (03/2022 - 09/2021)
7.	Yang, Chunsong: 2 articles (01/2022 - 01/2019)
8.	Egberts, K: 2 articles (08/2021 - 02/2021)
9.	Fekete, Stefanie: 2 articles (08/2021 - 02/2021)
10.	Gerlach, M: 2 articles (08/2021 - 02/2021)

Related Diseases

1.	Headache (Headaches) 12/30/1982 - "Tiapride proved effective in reducing the frequency of headache (in 65% of patients), with an improvement rate which was statistically significant in comparison to the placebo. " 05/18/1979 - "Tiapride seems more effective in early headache than in cephalalgia occuring later." 02/03/1983 - "To evaluate the effectiveness of intravenous tiapride in preventing cephalalgia following rachiocentesis, two groups of patients were studied in a double blind trial. " 10/18/1979 - "A therapeutic study was conducted by practitioners working in a group practice, to evaluate the activity of tiapride in treating headaches, over a period of 1 year. " 12/08/1978 - "The aim of this study was to try the efficiency of tiapridal in preventing headache during neuro-radiological procedures. "
2.	Alcoholism (Alcohol Abuse) 04/14/1983 - "Tiapride therefore proves a highly effective therapeutic agent in chronic alcoholism, providing rapid action, good results and excellent tolerance with small dosages." 10/31/1982 - "[Tiapride and alcoholism: evaluation of its therapeutic efficacy in 80 cases of alcoholic diseases]." 12/18/1981 - "Tiapride was effective against acute manifestations of alcoholism and against agitation, especially in the elderly. " 04/18/1979 - "It is true that the product was not associated systematically with psychotherapy which might have made the results more demonstrative, but the objective of the study was to evaluate whether tiapride could be of value by assisting in the fight against alcoholism, and this was confirmed." 05/01/1977 - "[Ambulatory trial of Tiapridal in chronic alcoholism]."
3.	Dyskinesias (Dyskinesia) 10/01/1985 - "The purpose of present study was to investigate efficacy and safety of Tiapride in patients with various forms of dyskinesia in long-term treatment. " 10/01/1985 - "[Long-term evaluation of tiapride in patients with various forms of dyskinesia]." 06/01/1983 - "Tiapride in doses not accompanied by significant recurrence of Parkinsonian symptoms revealed no significant diminution of the involuntary movements, and no effect on on-off periods was found." 12/09/1982 - "Tiapride was given at an average dosage of 300-900 mg per day, intramuscularly for the first three days, then by oral route, to 62 patients with abnormal movements of various types. " 03/25/1982 - "Twenty-five patients with various forms of dyskinesia were given tiapride for three months. "
4.	Tics (Tic) 02/01/2021 - "This study shows that tiapride treatment was effective and safe in most patients with tics. " 01/01/2016 - "While tics of all patients were reduced over time, 5-LGr and tiapride treatment produced significantly greater improvement on the YGTSS overall scale and subscale for TTS and impairment at endpoint than the placebo. " 03/01/2007 - "In Germany, tiapride seems to be used most often for the treatment of tics in children - although only one small controlled trial has been performed on it till now. " 01/01/1988 - "In order to study tiapride's antidyskinetic properties in the treatment of the tic syndrome in children, we conducted a simple, placebo-controlled study on 10 children followed by a double-blind crossover study on 17 children. " 02/01/2021 - "In addition, a preliminary therapeutic reference range for children and adolescents with tics treated with tiapride was calculated. "
5.	Pain (Aches) 11/18/1980 - "A study with tiapride demonstrated that this compound could be effective both for curative and preventive treatment, probably in relation to its direct action on pain centres. " 10/01/1995 - "Tiapride attenuates pain transmission through an indirect activation of central serotonergic mechanism." 10/21/1982 - "[Tiapride and pain in amputees]." 07/01/1982 - "[Modifications of (CNV) in patients with various types of pain treated with tiapride]." 03/08/1980 - "Tiapride was found to reduce pain and allow more effective physiotherapy to be applied with a more rapid return to work."

Related Drugs and Biologics

1.	Tetrabenazine (Nitoman)
2.	Antipsychotic Agents (Antipsychotics)
3.	metylperon (melperone)
4.	Risperidone (Risperdal Consta)
5.	benzamide
6.	Carbamazepine (Tegretol)
7.	Lorazepam (Ativan)
8.	Dopamine (Intropin)
9.	Clonazepam (Rivotril)
10.	Valproic Acid (Depakote)

Related Therapies and Procedures

1.	Therapeutics
2.	Aftercare (After-Treatment)
3.	Drug Therapy (Chemotherapy)
4.	Intravenous Injections
5.	Analgesia