L-Aminoadipate-Semialdehyde Dehydrogenase

An enzyme that catalyzes the oxidation of L-2-aminoadipate 6-semialdehyde to L-2-aminoadipate (alpha-aminoadipic acid). It is involved in the biosynthetic pathway of LYSINE.

Also Known As:

2-Aminoadipate Reductase; Aminoadipate-Semialdehyde Dehydrogenase; L-Aminoadipate Semialdehyde Dehydrogenase; alpha-Aminoadipate Reductase; alpha-Aminoadipate Reductase System; 2 Aminoadipate Reductase; Aminoadipate Semialdehyde Dehydrogenase; Dehydrogenase, Aminoadipate-Semialdehyde; Dehydrogenase, L-Aminoadipate Semialdehyde; Dehydrogenase, L-Aminoadipate-Semialdehyde; L Aminoadipate Semialdehyde Dehydrogenase; Reductase, 2-Aminoadipate; Reductase, alpha-Aminoadipate; alpha Aminoadipate Reductase; alpha Aminoadipate Reductase System

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Oxidoreductases Acting on Aldehyde or Oxo Group Donors
      - Aldehyde Oxidoreductases: 1
        L-Aminoadipate-Semialdehyde Dehydrogenase: 1
        human AASDH protein
        mouse Aasdh protein
        rat Aldh7a1 protein

Experts

1.	Aaltonen, Lauri A: 1 article (01/2017)
2.	Aavikko, Mervi: 1 article (01/2017)
3.	Böhm, Jan: 1 article (01/2017)
4.	Gylfe, Alexandra E: 1 article (01/2017)
5.	Hamberg, Jiri: 1 article (01/2017)
6.	Järvinen, Heikki: 1 article (01/2017)
7.	Kaasinen, Eevi: 1 article (01/2017)
8.	Katainen, Riku: 1 article (01/2017)
9.	Kondelin, Johanna: 1 article (01/2017)
10.	Lundgren, Sofie: 1 article (01/2017)

Related Diseases

Colorectal Neoplasms (Colorectal Cancer)

01/01/2017 - "Mutation significance and estimated clonality of mutations determined the most likely MSI target genes to be the aminoadipate-semialdehyde dehydrogenase AASDH and the solute transporter SLC9A8 Our findings offer a systematic profiling of the somatic background mutation rate in protein-coding mononucleotide microsatellites, allowing a full cataloging of the true targets of MSI in colorectal cancer. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)