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Neck Pain (Cervicalgia)

Discomfort or more intense forms of pain that are localized to the cervical region. This term generally refers to pain in the posterior or lateral regions of the neck.

Also Known As:

Cervicalgia; Neck Ache; Anterior Cervical Pain; Anterior Neck Pain; Cervicodynia; Posterior Cervical Pain; Posterior Neck Pain; Ache, Neck; Aches, Neck; Anterior Cervical Pains; Anterior Neck Pains; Cervical Pain, Anterior; Cervical Pain, Posterior; Cervical Pains; Cervical Pains, Anterior; Cervical Pains, Posterior; Cervicalgias; Cervicodynias; Neck Aches; Neck Pain, Anterior; Neck Pain, Posterior; Neck Pains; Neck Pains, Anterior; Neck Pains, Posterior; Neckaches; Pain, Anterior Cervical; Pain, Anterior Neck; Pain, Cervical; Pain, Neck; Pain, Posterior Cervical; Pain, Posterior Neck; Pains, Anterior Cervical; Pains, Anterior Neck; Pains, Cervical; Pains, Neck; Pains, Posterior Cervical; Pains, Posterior Neck; Posterior Cervical Pains; Posterior Neck Pains; Cervical Pain; Neckache

Networked: 794 relevant articles (139 outcomes, 141 trials/studies) for this Disease, Comments

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Pain (Aches)
2.	Low Back Pain (Lumbago)
3.	Headache (Headaches)
4.	Radiculopathy (Radiculopathy, Cervical)
5.	Shoulder Pain

Experts

1.	Jull, Gwendolen: 11 articles (09/2012 - 01/2002)
2.	van Tulder, Maurits W: 7 articles (11/2012 - 04/2003)
3.	Manchikanti, Laxmaiah: 7 articles (01/2012 - 04/2006)
4.	de Vet, Henrica C W: 6 articles (08/2011 - 05/2002)
5.	Bouter, Lex M: 6 articles (05/2010 - 05/2002)
6.	Koes, Bart W: 5 articles (11/2012 - 05/2002)
7.	Hurwitz, Eric L: 5 articles (10/2012 - 10/2002)
8.	Ylinen, Jari: 5 articles (01/2012 - 07/2004)
9.	Pampati, Vidyasagar: 5 articles (01/2012 - 04/2006)
10.	Kautiainen, Hannu: 5 articles (01/2012 - 07/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Neck Pain:

1.	SteroidsIBA 09/01/2010 - "To evaluate the clinical outcomes of therapeutic cervical medial branch blocks with local anesthetic with or without steroids in managing chronic neck pain of facet joint origin. " 05/01/2010 - "However, the literature supporting cervical interlaminar epidural steroids in managing chronic neck pain is scant. " 08/01/2008 - "Therapeutic cervical medial branch nerve blocks, with or without steroids, may provide effective management for chronic neck pain of facet joint origin." 01/01/2012 - "Cervical interlaminar epidural injections with local anesthetic with or without steroids were effective in 67% of patients overall and 87% in Group I and 72% in Group II, in successful group patients with chronic function-limiting neck pain and upper extremity pain secondary to cervical postsurgery syndrome. " 01/01/2012 - "To evaluate the effectiveness of cervical interlaminar epidural injections of local anesthetic with or without steroids in providing effective and long-lasting relief in the management of chronic neck pain and upper extremity pain in patients with cervical postsurgery syndrome, and to evaluate the differences between local anesthetic with or without steroids. " Order ALL the reference details at left...
2.	salicylhydroxamic acid (SHAM)IBA 01/01/2008 - "After a short course of NET treatment, measurements of visual analog scale and pressure algometer recordings of four trigger point locations in a cohort of chronic neck pain sufferers were significantly improved when compared to a control group which received a sham protocol of NET. " 01/01/2010 - "Efficacy of acupunture in patients with chronic neck pain--a randomised, sham controlled trial." 01/01/2012 - "By setting the control groups as sham and shallow acupuncture, this study attempts to reveal the effects of real acupuncture versus placebo or non-classic acupuncture treatment and evaluate whether classic Chinese medical acupuncture is effective on CS neck pain. " 05/01/2009 - "Electrical acustimulation of the wrist for chronic neck pain: a randomized, sham-controlled trial using a wrist-ankle acustimulation device." 09/01/2002 - "Thirty-six patients with chronic neck pain and limited cervical spine mobility participated in a prospective, randomized, double-blind, sham-controlled crossover trial. " Order ALL the reference details at left...
3.	Lidocaine (Xylocaine)FDA LinkGeneric 11/01/2010 - "A small amount of Lidocaine was injected at the left cervical 7 to test needle patency; she immediately complained of severe cervical pain radiated to the left upper and lower extremities. " 01/01/2010 - "PHN patients in the lidocaine patch group were older (64.5 vs. 62.2 years; p=0.002) and had higher rates of pain-related comorbidities (e.g., back/neck pain, osteoarthritis) than comparison patients. " 01/01/2007 - "In chronic neck disorders with radicular findings, epidural methylprednisolone and lidocaine reduced neck pain and improved function more than when given by intramuscular route at one-year follow-up, in one trial. " 05/01/2006 - "In chronic MND with radicular findings, epidural methylprednisolone and lidocaine reduced neck pain [SMD -1.46 (95% CI -2.16 to -0.76)] and improved function at one-year followup compared to the intramuscular route. " 01/01/2005 - "In chronic MND with radicular findings, epidural methylprednisolone and lidocaine reduced neck pain and improved function at one-year follow-up compared to the intramuscular route. " Order ALL the reference details at left...
4.	Methylprednisolone FDA LinkGeneric 01/01/2007 - "In chronic neck disorders with radicular findings, epidural methylprednisolone and lidocaine reduced neck pain and improved function more than when given by intramuscular route at one-year follow-up, in one trial. " 05/01/2006 - "In chronic MND with radicular findings, epidural methylprednisolone and lidocaine reduced neck pain [SMD -1.46 (95% CI -2.16 to -0.76)] and improved function at one-year followup compared to the intramuscular route. " 01/01/2005 - "In chronic MND with radicular findings, epidural methylprednisolone and lidocaine reduced neck pain and improved function at one-year follow-up compared to the intramuscular route. " Order ALL the reference details at left...
5.	Capsaicin (Zostrix)FDA Link 01/01/1995 - "This study demonstrated that topically applied capsaicin cream may decrease subjective neck pain. " 01/01/1995 - "Topical capsaicin for chronic neck pain. " 06/01/1998 - "Uncontrolled studies and case reports have indicated that pain or dysfunction was less at the end of capsaicin therapy for neck pain, loin pain/hematuria syndrome, oral mucositis, rhinopathy, reflex sympathetic dystrophy syndrome, detrusor hyperreflexia, and cutaneous pain due to tumor of the skin. " 06/01/1998 - "Capsaicin is effective for psoriasis, pruritus, and cluster headache; it is often helpful for the itching and pain of postmastectomy pain syndrome, oral mucositis, cutaneous allergy, loin pain/hematuria syndrome, neck pain, amputation stump pain, and skin tumor; and it may be beneficial for neural dysfunction (detrusor hyperreflexia, reflex sympathetic dystrophy, and rhinopathy). " 07/01/2012 - "The objective of this study was to evaluate the efficacy of a hydrogel patch containing capsaicin 0.1% compared with a placebo hydrogel patch without capsaicin to treat chronic myofascial neck pain. " Order ALL the reference details at left...
6.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 02/01/2009 - "In Canada and the United States, the most commonly prescribed neck pain treatments are nonsteroidal anti-inflammatory drugs (NSAIDs), exercise, and manual therapy. " 02/15/2008 - "In Canada and the United States, the most commonly prescribed neck pain treatments are nonsteroidal anti-inflammatory drugs (NSAIDs), exercise, and manual therapy. " 06/01/1996 - "A risk assessment of cervical manipulation vs. NSAIDs for the treatment of neck pain." 03/01/1996 - "A risk assessment of spinal manipulation vs. NSAIDs for the treatment of neck pain." 10/01/1995 - "A risk assessment of cervical manipulation vs. NSAIDs for the treatment of neck pain." Order ALL the reference details at left...
7.	PlasticsIBA 09/01/1995 - "VH might have been the result of plastic adaptation to limited head mobility secondary to neck pain. " 01/01/1995 - "The hyperactive VOR might have been the result of plastic adaptation to limited head mobility secondary to neck pain. " 03/01/2010 - "Reduction mammaplasty is a common procedure performed by plastic and reconstructive surgeons to relieve chronic back and neck pain associated with macromastia, with the added benefit of an improvement in the aesthetic contour of the ptotic breast. " 05/01/1989 - "Ventral decompression or linear traction and plastic plate stabilization were effective in the treatment of most patients with mild to moderate neurologic deficits (neck pain, paraparesis, or ambulatory tetraparesis). " Order ALL the reference details at left...
8.	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 04/01/2004 - "Nocturnal neck pain relieved by aspirin." 10/01/2012 - "In the case of persistent neck pain, not readily relieved by aspirin and possibly accompanied by stiffness, scoliosis or neurological deficits, especially in young subjects, osteoblastoma of cervical spine may be one of the diagnostic options to be considered, in order to avoid delay in diagnosis. " 08/10/2006 - "A right-handed woman of 90, taking aspirin 160 mg daily, suffered acute neck pain radiating to the shoulders, with right side hemiparesis and numbness occurring minutes thereafter. " Order ALL the reference details at left...
9.	Amitriptyline (Elavil)FDA LinkGeneric 01/01/2001 - "Forty non-depressed patients, suffering from low back pain and whiplash associated cervical pain were enrolled in a randomized, six-week, "blind-rater" study, comparing the analgesic effect of amitriptyline (50-75 mgs/day) with that of fluoxetine (20 mgs/day). " 01/01/2001 - "In our study, fluoxetine relieved low back pain and whiplash associated cervical pain with efficacy similar to that of amitriptyline, offering an alternative for patients unable to tolerate the tricyclic antidepressants' side effects." 07/01/2008 - "A 60-year-old man developed postsurgical neuropathic cervical pain treated by hydromorphone, gabapentin, clonazepam, and amitriptyline. " Order ALL the reference details at left...
10.	TNFR-Fc fusion protein (etanercept)FDA Link 07/01/2004 - "The medical charts of all patients who were treated with etanercept for back or neck pain at a single private medical clinic in 2003 were reviewed retrospectively. " 07/01/2004 - "Documentation of the clinical results obtained utilizing perispinal etanercept off-label for treatment-refractory back and neck pain in a clinical practice setting. " 04/01/2003 - "Targeted etanercept for discogenic neck pain: uncontrolled, open-label results in two adults." 04/01/2003 - "This study reviews findings from 2 patients with chronic, severe, discogenic cervical pain who were treated with a targeted cervical injection of etanercept with the objective of obtaining relief from their treatment-resistant pain. " Order ALL the reference details at left...

Therapies and Procedures

1.	Spinal Manipulation 12/01/2008 - "Only 1 study has examined the association between adverse events and outcome in subjects with neck pain treated by chiropractors, which concluded that those receiving cervical spinal manipulation were more likely to report an adverse event compared to cervical mobilization, and those reporting an adverse event were less likely to have improved outcomes at all follow-up measurements. " 01/01/2001 - "Spinal manipulation and exercise for chronic neck pain: are they more effective when delivered alone or in combination?" 01/03/2012 - "Summaries for patients: is spinal manipulation an effective treatment for neck pain?" 11/01/2006 - "Cervical manipulation has been considered an effective treatment for managing neck pain. " 10/01/1995 - "We reviewed the literature to evaluate the risk of serious injury or death resulting from cervical manipulation and to assess the evidence that cervical manipulation is an effective treatment for mechanical neck pain. " Order ALL the reference details at left...
2.	Musculoskeletal Manipulations (Manipulative Therapy) 01/01/2002 - "Each study has its strengths and weaknesses, but the most powerful ones indicate that manual techniques are beneficial for back and neck pain when compared with no treatment or "placebo." Comparative studies against other techniques such as physical therapy, education, or exercise do not show a clear superiority for manual therapy, however. " 01/01/2011 - "Evidence indicates that supervised home exercises, combined or not with manual therapy, can be beneficial for patients with non-specific chronic neck pain (NCNP). " 08/15/2011 - "Is behavioral graded activity cost-effective in comparison with manual therapy for patients with subacute neck pain? " 01/01/2010 - "Combined manual therapy, like naprapathy, is effective in the short and in the long term, and might be considered for patients with non-specific back and/or neck pain. " 02/01/2007 - "There are multiple reports in the literature of serious and at times fatal complications after cervical spine manipulation therapy (CSMT), even though CSMT is considered by some health providers to be an effective and safe therapeutic procedure for head and neck pain syndromes. " Order ALL the reference details at left...
3.	Massage (Reflexology) 10/01/2010 - "Although most people chose self-massage to be the most effective self-care treatment, only one-third (30.2%) of them had their neck pain improved by less than a half. " 07/01/2003 - "The results of the study indicate that acupuncture is superior to conventional massage for improving active range of motion in patients with chronic neck pain. " 07/01/2012 - "The Ottawa Panel was able to demonstrate that the massage interventions are effective for relieving immediate post-treatment neck pain symptoms, but data is insufficient for long-term effects." 01/01/2011 - "A novel massage therapy technique for management of chronic cervical pain: a case series." 06/30/2001 - "To compare the efficacy of acupuncture and conventional massage for the treatment of chronic neck pain. " Order ALL the reference details at left...
4.	Traction 06/01/2011 - "The objective of the study was to identify the population of patients with neck pain who improved with home-based mechanical cervical traction (HMCT). " 02/01/1995 - "The available reports of studies on the efficacy of traction for back and neck pain do not allow clear conclusions due to the methodological flaws in their design and conduct. " 09/01/2011 - "To investigate the efficacy of intermittent cervical traction in the treatment of chronic neck pain over a 12-week follow-up. " 09/01/2011 - "A randomized controlled trial on the efficacy of intermittent cervical traction for patients with chronic neck pain." 10/01/2008 - "The efficacy of intermittent cervical traction in patents with chronic neck pain." Order ALL the reference details at left...
5.	Epidural Injections 01/01/2012 - "Despite limited evidence, cervical epidural injections are one of the commonly performed nonsurgical interventions in the management of chronic neck pain. " 07/01/2010 - "Despite limited evidence, cervical epidural injections are one of the commonly performed non-surgical interventions in the management of chronic neck pain. " 07/01/2012 - "Cervical epidural injections for managing chronic neck pain are one of the commonly performed interventions in the United States. " 11/01/2010 - "A 56-year-old woman with chronic cervical pain underwent an elective cervical epidural injection. " 05/01/2010 - "Cervical epidural injections for managing chronic neck pain with disc herniation are one of the commonly performed non-surgical interventions in the United States. " Order ALL the reference details at left...

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