Hemodiafiltration

The combination of hemodialysis and hemofiltration either simultaneously or sequentially. Convective transport (hemofiltration) may be better for removal of larger molecular weight substances and diffusive transport (hemodialysis) for smaller molecular weight solutes.

Also Known As:

Networked: 822 relevant articles (68 outcomes, 90 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Oda, Shigeto: 28 articles (02/2021 - 01/2002)
2.	Hirasawa, Hiroyuki: 23 articles (04/2014 - 01/2002)
3.	Canaud, Bernard: 20 articles (01/2022 - 01/2004)
4.	Nakamura, Masataka: 15 articles (01/2014 - 06/2002)
5.	Matsuda, Kenichi: 12 articles (12/2017 - 12/2002)
6.	Shiga, Hidetoshi: 12 articles (01/2014 - 01/2002)
7.	Blankestijn, Peter J: 11 articles (01/2022 - 01/2011)
8.	Abe, Ryuzo: 11 articles (03/2020 - 01/2002)
9.	Davenport, Andrew: 10 articles (12/2022 - 07/2008)
10.	Grooteman, Muriel P C: 9 articles (01/2022 - 01/2011)

Related Diseases

1.	Acute Kidney Injury (Acute Renal Failure) 01/01/2006 - "All patients were successfully cured of acute renal failure by hemodialysis or hemodiafiltration. " 01/01/1987 - "Bag-filter hemodiafiltration (BF-HDF): simple and effective treatment of acute renal failure." 05/09/2023 - "The next day, he developed multi-organ failure and was started on hemodiafiltration (HDF) for acute kidney injury. " 01/01/2023 - "Switching from continuous veno-venous hemodiafiltration to intermittent sustained low-efficiency daily hemodiafiltration (SLED-f) in pediatric acute kidney injury: A prospective cohort study." 09/01/2022 - "Intermittent Online Postdilution Hemodiafiltration versus High-Flux Hemodialysis in Non-critical Acute Kidney Injury: A Pilot Randomized Controlled Trial."
2.	Chronic Kidney Failure (Chronic Renal Failure) 01/01/2022 - "Conventional hemodialysis does not improve RBC lifespan; the efficacy of hemodiafiltration (HDF) for alleviating RBC lifespan has not yet been evaluated in patients with ESRD. " 01/01/2004 - "Hemodiafiltration (HDF) is a well-recognized treatment modality that offers a way of optimizing renal replacement therapy efficacy of end-stage renal disease (ESRD) patients. " 02/17/2023 - "This study aimed to investigate the correlation between beta-2 microglobulin (B2M) concentration and some nerve conduction indices and evaluate the changes in some nerve conduction indices after treatment with hemodialysis (HD) combined with hemodiafiltration online in end-stage renal disease patients. " 01/01/2023 - "We analyzed baseline data (N = 1,113) from the CONVINCE study, an international trial in end-stage kidney disease patients comparing high-dose hemodiafiltration with high-flux hemodialysis. " 01/01/2021 - "The Filtration in the Neuropathy of End-Stage Kidney Disease Symptom Evolution (FINESSE) study was an open-label, blinded end point assessment, controlled trial that randomized maintenance hemodialysis recipients to hemodiafiltration or high-flux hemodialysis for 48 months or until death or cessation of dialysis at four study centers. "
3.	Inflammation (Inflammations) 01/01/2018 - "Hemodiafiltration is associated with reduced inflammation, oxidative stress and improved endothelial risk profile compared to high-flux hemodialysis in children." 01/01/2015 - "On-line hemodiafiltration (OL-HDF) can achieve a considerable clearance of middle molecules and, together with its sterile ultrapure infusate, may have favorable effects on inflammation and cardiovascular complications. " 01/01/2017 - "In an attempt to reduce inflammation and thus cardiovascular toxicity in patients with ESKD, hemodiafiltration (HDF) has been promoted to enhance the clearance of middle molecular weight substances during dialysis. " 01/01/2016 - "Retraction notice to “Continuous Hemodiafiltration Therapy Ameliorates LPS-Induced Systemic Inflammation in a Rat Model” J Surg Res 171 (2011) 791-796." 09/01/2021 - "Hemodiafiltration Is Associated With Reduced Inflammation and Increased Bone Formation Compared With Conventional Hemodialysis in Children: The HDF, Hearts and Heights (3H) Study."
4.	Cytokine Release Syndrome 10/01/2001 - "After plasma exchange and continuous hemodiafiltration were started, hypercytokinemia and vital signs improved dramatically. " 11/01/2021 - "Continuous Hemodiafiltration with the oXiris Filter Ameliorates Cytokine Storm and Induces Rapid Clinical Improvement in COVID-19 - A Case Report." 02/01/2009 - "To examine the role of hypercytokinemia in the pathophysiology of tumor lysis syndrome (TLS) and the efficacy of continuous hemodiafiltration in the treatment of TLS. " 01/01/2015 - "Continuous hemodiafiltration (CHDF) is used as renal replacement therapy for critically ill patients with renal failure, and to treat hypercytokinemia. " 04/01/2014 - "Efficacy of series double continuous hemodiafiltration using two polymethyl methacrylate membrane hemofilters for patients with hypercytokinemia."
5.	Hypotension (Low Blood Pressure) 01/01/2017 - "show that hemodiafiltration may prevent intradialytic hypotension, albeit in a study that also has some shortcomings. " 01/27/2023 - "Many hypotheses could explain the mortality decrease observed using hemodiafiltration, such as reduction of intradialytic hypotension and more efficient toxin removal. " 01/01/2019 - "Compared with hemodialysis (HD), hemodiafiltration (HDF) reduces the frequency of episodes of intradialytic hypotension. " 01/01/2018 - "Hemodiafiltration is also associated with improvements in other clinical outcomes, such as a reduction in intradialytic hypotension, and it is now used routinely to treat >100,000 patients, mainly in Europe and Japan." 01/01/2018 - "The evidence concerning online hemodiafiltration (HDF) includes the following: (1) the increase of removal of uremic toxin, (2) the prevention of dialysis rerated hypotension, (3) the recovery of survival, and (4) the recovery of dialysis related uncertain symptoms. "

Related Drugs and Biologics

1.	Polymyxin B (Aerosporin)
2.	Polymethyl Methacrylate (Sol)
3.	Cytokines
4.	Dialysis Solutions
5.	Steroids
6.	Albumins
7.	Citric Acid (Citrate)
8.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
9.	Proteins (Proteins, Gene)
10.	Interleukin-6 (Interleukin 6)

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)
2.	Therapeutics
3.	Plasma Exchange
4.	Renal Replacement Therapy (Therapies, Renal Replacement)
5.	Continuous Renal Replacement Therapy