A chronic, congenital ichthyosis inherited as an autosomal recessive trait. Infants are usually born encased in a collodion membrane which sheds within a few weeks. Scaling is generalized and marked with grayish-brown quadrilateral scales, adherent at their centers and free at the edges. In some cases, scales are so thick that they resemble armored plate.
Also Known As:
Harlequin Ichthyosis; Harlequin Fetus; Ichthyosis, Lamellar; Collodion Baby Syndrome; Collodion Fetus; Congenital Ichthyosiform Erythroderma, Nonbullous; Congenital Nonbullous Ichthyosiform Erythroderma; Desquamation of Newborn; Harlequin Baby Syndrome; Ichthyoses, Lamellar; Ichthyosis Congenita; Ichthyosis Congenita I; Ichthyosis Congenita II; Ichthyosis, Lamellar, 1; Lamellar Exfoliation of Newborn; Lamellar Ichthyoses; Lamellar Ichthyosis, Type 1; Nonbullous Congenital Ichthyosiform Erythroderma; Nonbullous Congenital Lamellar Ichthyosis; Baby Syndrome, Collodion; Baby Syndrome, Harlequin; Baby Syndromes, Collodion; Baby Syndromes, Harlequin; Collodion Baby Syndromes; Congenita II, Ichthyosis; Congenita IIs, Ichthyosis; Erythroderma Ichthyosiformes, Nonbullous; Fetus, Collodion; Fetus, Harlequin; Harlequin Baby Syndromes; Harlequin Ichthyoses; Ichthyose, Lamellar; Ichthyoses, Harlequin; Ichthyosiforme, Nonbullous Erythroderma; Ichthyosiformes, Nonbullous Erythroderma; Ichthyosis Congenita IIs; Ichthyosis, Harlequin; Lamellar Ichthyose; Newborn Desquamation; Newborn Desquamations; Newborn Lamellar Exfoliation; Newborn Lamellar Exfoliations; Nonbullous Erythroderma Ichthyosiforme; Nonbullous Erythroderma Ichthyosiformes; Syndrome, Collodion Baby; Syndrome, Harlequin Baby; Syndromes, Collodion Baby; Syndromes, Harlequin Baby; Erythroderma Ichthyosiforme, Nonbullous; Ichthyosiform Erythroderma, Nonbullous Congenital