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Desipramine (Pertofrane)

A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
Also Known As:
Pertofrane; Norpramin; Apo-Desipramine; Apotex Brand of Desipramine Hydrochloride; Aventis Behring Brand of Desipramine Hydrochloride; Aventis Brand of Desipramine Hydrochloride; Demethylimipramine; Desipramine Hydrochloride; Novartis Brand of Desipramine Hydrochloride; Novo-Desipramine; Novopharm Brand of Desipramine Hydrochloride; Nu-Desipramine; Nu-Pharm Brand of Desipramine Hydrochloride; PMS-Desipramine; Pertofran; Pertrofran; Petylyl; Pharmascience Brand of Desipramine Hydrochloride; Ratiopharm Brand of Desipramine Hydrochloride; Rhône-Poulenc Rorer Brand of Desipramine Hydrochloride; Temmler Brand of Desipramine Hydrochloride; ratio-Desipramine; Hydrochloride, Desipramine; Nu Pharm Brand of Desipramine Hydrochloride; Rhône Poulenc Rorer Brand of Desipramine Hydrochloride; Desmethylimipramine; 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-
Networked: 709 relevant articles (66 outcomes, 121 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Kubera, Marta: 5 articles (03/2014 - 11/2009)
2. Jan, Chung-Ren: 4 articles (03/2009 - 12/2003)
3. Oliveto, Alison: 4 articles (01/2005 - 01/2002)
4. Popoli, Maurizio: 3 articles (02/2015 - 03/2003)
5. Wrona, Danuta: 3 articles (03/2014 - 12/2011)
6. Qi, Hong: 3 articles (02/2013 - 09/2002)
7. Chen, Hong-Zhuan: 3 articles (02/2013 - 09/2002)
8. Basta-Kaim, Agnieszka: 3 articles (01/2013 - 11/2009)
9. Grygier, Beata: 3 articles (01/2013 - 11/2009)
10. Budziszewska, Bogusława: 3 articles (01/2013 - 11/2009)

Related Diseases

1. Pain (Aches)
2. Neuralgia (Stump Neuralgia)
3. Panic Disorder (Panic Attack)
4. Cocaine-Related Disorders (Cocaine Addiction)
5. Tics (Tic)

Related Drugs and Biologics

1. Amitriptyline (Elavil)
2. Tricyclic Antidepressive Agents (Tricyclic Antidepressants)
3. Clomipramine (Anafranil)
4. Imipramine (Janimine)
5. Fluoxetine (Prozac)
6. Serotonin (5 Hydroxytryptamine)
7. Nortriptyline (Aventyl)
8. Antidepressive Agents (Antidepressants)
9. Methadone (Dolophine)
10. Cocaine (Cocaine HCl)

Related Therapies and Procedures

1. Analgesia
2. Ligation
3. Oral Administration
4. Aftercare (After-Treatment)
5. Induced Hypothermia