Puberty Suppression

A non-intensive, reversible medical intervention achieved by using compounds that mimic the actions of GONADOTROPIN-RELEASING HORMONE (GnRH), which in turn slows or stops the physical changes associated with puberty such as the development of breasts or facial hair.

Also Known As:

Networked: 30 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Cohen-Kettenis, Peggy T: 5 articles (01/2018 - 05/2011)
2.	Steensma, Thomas D: 3 articles (11/2020 - 08/2011)
3.	de Vries, Annelou L C: 3 articles (11/2020 - 08/2011)
4.	Carmichael, Polly: 3 articles (01/2019 - 11/2015)
5.	Fahrenkrug, Saskia: 2 articles (11/2021 - 01/2014)
6.	Richter-Appelt, Hertha: 2 articles (11/2021 - 01/2014)
7.	Schagen, Sebastian E E: 2 articles (01/2018 - 06/2015)
8.	Colizzi, Marco: 2 articles (01/2016 - 11/2015)
9.	Costa, Rosalia: 2 articles (01/2016 - 11/2015)
10.	Briken, Peer: 2 articles (11/2015 - 01/2014)

Related Diseases

1.	Gender Dysphoria 01/01/2021 - "The majority (71%) of participants in these studies required a diagnosis of gender dysphoria to qualify for puberty suppression and were administered medication during Tanner stages 2 through 4. Positive outcomes were decreased suicidality in adulthood, improved affect and psychological functioning, and improved social life. " 07/09/2019 - "The study uses a longitudinal observational design to examine the outcomes of existing medical treatment protocols for gender dysphoria in two distinct cohorts: youth initiating puberty suppression and youth pursuing a phenotypic gender transition. " 06/01/2015 - "Puberty suppression and executive functioning: An fMRI-study in adolescents with gender dysphoria." 12/01/2023 - "A total of 75 participants diagnosed with gender dysphoria who had used puberty suppression before age 18 years prior to receiving at least 9 years of long-term GAH were included. " 01/01/2023 - "It has been a quarter of a century since Dutch clinicians proposed puberty suppression as an intervention for "juvenile transsexuals," which became the international standard for treating gender dysphoria. "
2.	Precocious Puberty 01/01/2023 - "Gonadotrophin-releasing hormone agonists (GnRHas) are used for puberty suppression in central precocious puberty (CPP) and gender dysphoria (GD). "
3.	Gynecomastia 11/01/2021 - "Transgender boys who undergo GnRH agonist treatment for puberty suppression and subsequently receive testosterone therapy for puberty induction may develop gynecomastia. "
4.	Autistic Disorder (Autism) 06/01/2021 - "A Longitudinal Study of Features Associated with Autism Spectrum in Clinic Referred, Gender Diverse Adolescents Accessing Puberty Suppression Treatment."

Related Drugs and Biologics

1.	Gonadotropin-Releasing Hormone (GnRH)
2.	Hormones (Hormone)
3.	Testosterone (Sustanon)
4.	Estradiol (Delestrogen)
5.	Gonadal Steroid Hormones (Sex Hormones)
6.	Leuprolide (Lupron)
7.	Androgens
8.	6-chloro-2-(1-piperazinyl)pyrazine (CPP)

Related Therapies and Procedures

1.	Therapeutics
2.	Sex Reassignment Surgery