Myokines

12/01/2016 - "Enhanced muscle strength is often related to improved insulin sensitivity and secretion, control of lipid metabolism, and increased secretion of myokines. "
01/01/2015 - "Irisin, a circulating myokine, stimulates "browning" of white adipose tissue resulting in increased energy expenditure and improved insulin sensitivity. "
01/01/2015 - "On the other hand, several studies have shown that insulin resistance in the skeletal muscle may change myokines expression and secretion. "
01/01/2013 - "This study provides evidence that the FNDC5 gene, encoding the novel myokine irisin, determines insulin sensitivity in humans. "
04/22/2022 - "Mechanisms by Which Skeletal Muscle Myokines Ameliorate Insulin Resistance."

09/13/2022 - "Irisin, as one of the myokines induced by exercise, has attracted much attention due to its important physiological functions such as white fat browning, the improvement in metabolism, and the alleviation of inflammation. "
12/07/2018 - "These data indicate that myonectin functions as an endurance exercise-induced myokine which ameliorates acute myocardial ischemic injury by suppressing apoptosis and inflammation in the heart, suggesting that myonectin mediates some of the beneficial actions of exercise on cardiovascular health."
02/27/2023 - "Using control or transgenic mice with TGF-βr2 deleted in skeletal muscle (SM TGF-βr2-/-) and the derived primary differentiating myogenic precursor cells (MPCs) treated with/without ERS activator or inhibitor, IRE1α pathway inhibitor, or TGF-β signaling activator, this study further revealed an essential role of intrinsic TGF-β signaling in regulating muscle cell to express inflammation-related molecules including H-2Kb, H2-Eα, TLR3, and special myokines. "
01/01/2023 - "This study suggests that moderate PA could counteract the elevated BP induced by PM2.5 exposure via myokines-suppressed inflammation pathways."
01/01/2023 - "We aimed to evaluate whether moderate physical activity (PA) protected BP health against PM2.5 exposure and explore potential mechanisms through myokines and inflammation. "

10/02/2023 - "This study aimed to identify the characteristics of myokines and independent predictors of serum FST levels in patients with obesity. "
08/01/2023 - "The aim of our study was to evaluate the effect of physical exercise on myokine levels, anthropometric parameters, clinical data, impedance parameters, and muscle ultrasound data in sedentary females with obesity. "
01/01/2023 - "Our study provides a novel CRISPR-based myokines activation strategy that can ameliorate obesity by promoting adipocytes browning."
01/01/2023 - "This study aimed to evaluate the therapeutic potential of a novel CRISPR-based myokines activation strategy in obesity treatments. "
01/01/2022 - "to study the features of the secretion of myokines in children with constitutionally exogenous obesity during physical activity of different duration and intensity and to evaluate their relationship with the parameters of the body composition. "

08/01/2014 - "It has been suggested that myokines may contribute to exercise-induced protection against several chronic disease. "
01/15/2011 - "It has been suggested that myokines may contribute to exercise-induced protection against several chronic diseases."
07/01/2020 - "In recent years, scientific interest has been developed towards irisin, a novel molecule of the family of myokines, which is directly involved in body mass composition balance, chronic diseases susceptibility and physiologic resilience to stressful events, including surgery. "
01/01/2020 - "Myokine Irisin has been proposed to regulate metabolic homeostasis, which is related to chronic diseases or physical activity. "
01/01/2019 - "Neuromuscular Electrical Stimulation: A New Therapeutic Option for Chronic Diseases Based on Contraction-Induced Myokine Secretion."

01/01/2017 - "Irisin, as a myokine, is considered to be therapeutic for human metabolic diseases. "
12/01/2014 - "Numerous studies on myokines suggested that myokines offer a potential treatment option for preventing metabolic diseases. "
11/05/2022 - "The myokine irisin reportedly promotes positive outcomes in metabolic disease. "
06/01/2022 - "Evidence suggests that myokines could have clinical implications for metabolic diseases such as type-2 diabetes. "
01/01/2021 - "Moreover, we clarify the connection between exercise, myokines and disease development, which may contribute to the understanding of a potential mechanism by which physical inactivity affects the process of metabolic diseases via myokines. "