Polyether Toxins

Polycyclic polyether polyketides most often produced by marine organisms, e.g., DINOFLAGELLATES. Many polyether marine toxins are ionophores and neurotoxins and responsible for seafood poisoning.

Also Known As:

Networked: 28 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ramsdell, John S: 3 articles (11/2009 - 06/2007)
2.	Lewis, Richard J: 2 articles (01/2016 - 07/2009)
3.	Vetter, Irina: 2 articles (01/2016 - 12/2014)
4.	Krock, Bernd: 2 articles (12/2014 - 10/2012)
5.	García, Carlos: 2 articles (02/2004 - 01/2003)
6.	Lagos, Néstor: 2 articles (02/2004 - 01/2003)
7.	James, Kevin J: 2 articles (01/2004 - 12/2003)
8.	Fernández, J J: 2 articles (01/2002 - 05/2001)
9.	Norte, M: 2 articles (01/2002 - 05/2001)
10.	Souto, M L: 2 articles (01/2002 - 05/2001)

Related Diseases

1.	Shellfish Poisoning 10/01/2012 - "Azaspiracids (AZAs) are a group of lipophilic polyether toxins implicated in incidents of shellfish poisoning in humans, particularly in northern Europe, which are produced by the small marine dinoflagellate Azadinium spinosum. " 12/01/2003 - "The human toxic syndrome, diarrhetic shellfish poisoning (DSP), is caused by polyether toxins that are present in bivalve molluscs but originate from some species of marine phytoplankton. " 01/01/2002 - "It was the first example of a group of polyether toxins produced by marine microalgae, which is responsible for the natural phenomena known as Diarrhetic Shellfish Poisoning, DSP red tides. " 05/01/1999 - "The ecophysiology, biosynthesis, and metabolism of polyether toxins and paralytic shellfish poisoning (PSP) toxins were also reviewed. " 01/01/1996 - "Biosynthetic mechanisms of certain metabolites such as paralytic shellfish poisoning toxins and polyether toxins are also discussed, and genetic aspects of the secondary metabolite production as well."
2.	Ciguatera Poisoning (Ciguatera) 01/01/2002 - "Ciguatera fish poisoning arises from consumption of any of the 400 species of tropical marine reef fish containing polyether toxins. " 01/01/2016 - "The ability to rapidly identify polyether toxins produced by Gambierdiscus spp. in culture has the potential to distinguish ciguatoxin-producing species prior to large-scale culture and in naturally occurring blooms of Gambierdiscus and Fukuyoa spp. Our results have implications for the evaluation of ciguatera risk associated with Gambierdiscus and related species." 12/01/2014 - "Microalgae belonging to the family of flagellate protists, in particular dinoflagellates, secrete a variety of high-molecular-weight polyether toxins that accumulate through the marine food chain to cause disease in humans by acting as sodium channel activator toxins; ciguatera is the most frequent seafood-borne illness worldwide with 50,000 to 500,000 global incidences per annum and is usually limited to endemic areas located between 35° northern and 35° southern latitude. " 07/15/2010 - "Ciguatera fish poisoning (CFP) is a human foodborne intoxication caused by ingestion of tropical fishes contaminated with the potent polyether toxins known as ciguatoxins (CTXs). " 01/01/1999 - "The aim of the present review was to collect the main observations reported until now concerning the cardio-circulatory effects of polyether toxins, called ciguatoxins, which are involved in an endemic intoxication named ciguatera found in tropical and subtropical countries. "
3.	Foodborne Diseases 01/01/2016 - "Marine ladder-shaped polyether toxins are implicated in neurological symptoms of fish-borne food poisonings. " 06/01/2009 - "Azaspiracids (AZAs) are a group of lipophilic polyether toxins that were discovered in shellfish from Ireland in 1995, following a food poisoning incident. " 01/23/2004 - "Azaspiracids (AZAs) are a group of polyether toxins that cause food poisoning in humans. " 02/01/2013 - "Neurotoxic shellfish poisoning is a significant food-borne disease caused by potent cyclic polyether toxins (brevetoxins) that accumulate in the flesh of shellfish. " 07/01/2009 - "Ciguatera is a significant food borne disease caused by potent polyether toxins known as ciguatoxins, which accumulate in the flesh of ciguateric fish at risk levels above 0.1 ppb. "
4.	Poisoning 10/09/2021 - "The consumption of shellfish contaminated with brevetoxins, a family of ladder-frame polyether toxins formed during blooms of the marine dinoflagellate Karenia brevis, can cause neurotoxic poisoning, leading to gastroenteritis and neurotoxic effects. " 01/26/2001 - "Along with some polyether toxins of DSP (diarrhetic shellfish poisoning) type, such as yessotoxin and its analogues, which are responsible for a variety of human seafood poisonings throughout the world, we have now isolated a new type of toxin, the chlorosulfolipid 1, which is completely different in structure from the polyether DSP-toxins isolated so far. " 11/01/2007 - "Ciguatoxins (CTX) are a suite of cyclic polyether toxins produced by the marine dinoflagellate Gambierdiscus sp., are potent activators of voltage-gated sodium channels and a leading cause of human poisoning from food fish. "
5.	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 02/01/2004 - "Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disease caused by fat-soluble polyether toxins produced by dinoflagellates and accumulated in shellfish. " 01/01/2003 - "Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disease caused by lipid soluble polyether toxins produced by dinoflagellates and accumulated in shellfish. "

Related Drugs and Biologics

1.	Ciguatoxins
2.	Okadaic Acid
3.	Sodium Channels (Sodium Channel)
4.	Lipids
5.	Voltage-Gated Sodium Channels
6.	yessotoxin