Wrist Fractures

Fractures of the CARPAL BONES, the distal ULNA and/or RADIUS at the WRIST.

Also Known As:

Distal Forearm Fracture; Distal Radius Fracture; Distal Ulna Fracture; Forearm Fracture, Distal; Fracture, Distal Forearm; Fracture, Distal Radius; Fracture, Distal Ulna; Fracture, Radial Styloid; Fracture, Smith; Fracture, Wrist; Radial Styloid Fracture; Radius Fracture, Distal; Styloid Fracture, Radial; Ulna Fracture, Distal; Wrist Fracture; Distal Forearm Fractures; Distal Radius Fractures; Distal Radius and Ulna Fractures; Distal Ulna Fractures; Distal Ulna and Radius Fractures; Radial Styloid Fractures; Smith Fracture

Networked: 1294 relevant articles (70 outcomes, 257 trials/studies)

Relationship Network

Disease Context: Research Results

Wounds and Injuries: 176426
- Bone Fractures: 3857
  - Wrist Fractures: 1294
- Arm Injuries: 16
  - Wrist Injuries: 64
    - Wrist Fractures: 1294

Related Diseases

1.	Pain (Aches)
2.	Complex Regional Pain Syndromes
3.	Hematoma
4.	Osteoporosis
5.	Postoperative Pain

Experts

1.	Chung, Kevin C: 12 articles (01/2021 - 06/2002)
2.	Ilyas, Asif M: 10 articles (04/2022 - 04/2007)
3.	Ruch, David S: 7 articles (01/2022 - 01/2010)
4.	Catani, Fabio: 7 articles (10/2020 - 03/2013)
5.	Tarallo, Luigi: 7 articles (10/2020 - 03/2013)
6.	Ring, David: 7 articles (08/2020 - 03/2010)
7.	Chen, Alvin Chao-Yu: 7 articles (05/2019 - 08/2006)
8.	Adani, Roberto: 6 articles (12/2019 - 03/2013)
9.	Jupiter, Jesse B: 6 articles (04/2019 - 09/2005)
10.	Mugnai, Raffaele: 6 articles (10/2018 - 03/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Wrist Fractures:

1.	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/01/2009 - "Vitamin C has been shown to be effective in preventing CRPS I secondary to wrist fracture, but few data are available with respect to foot and ankle cases. " 05/01/2021 - "This study aimed to evaluate the effect of regional vitamin C in Bier block in the early phase of fracture on CRPS occurrence following surgery for distal radius fractures. " 01/01/2017 - "Randomised, placebo-controlled trials of vitamin C to prevent CRPS-I after wrist fractures were sought in the three main databases: PubMed (1980 to December 2015), CENTRAL (Central 2015, number 12), and Embase (1980 to December 2015). " 08/01/2015 - "Across 3 trials (n = 890) of patients with distal radius fractures, vitamin C did not reduce the risk for CRPS (risk ratio = 0.45; 95% confidence interval, 0.18-1.13; I = 70%). " 03/03/2023 - "Vitamin C was prescribed in 50% of EDs after a wrist fracture. "
2.	Opioid Analgesics (Opioids)IBA 04/01/2023 - "This study found a significant reduction in opioid volume in patients with a diagnosis of cannabis use who filled an opioid prescription after open reduction and internal fixation of distal radius fractures. " 01/01/2021 - "To identify targets for corrective interventions and guide improved opioid stewardship, we studied opioid prescribing patterns of attending surgeons compared with surgical trainees for 2 upper-extremity surgeries: open reduction internal fixation (ORIF) of distal radius fractures (DRF), and carpal tunnel release (CTR). " 05/01/2023 - "The purpose of this study was to investigate opioid prescription patterns after distal radius fracture fixation and identify patient-specific risk factors associated with increased opioid prescription refills. " 04/01/2023 - "The purpose of this study was to evaluate opioid demand after open reduction and internal fixation of distal radius fractures in patients with and without a diagnosis of cannabis use. " 03/22/2023 - "The purpose of this study was to determine the influence of chronic preoperative opioid use on complications, reoperation rates, and postoperative opioid use among patients undergoing open reduction and internal fixation (ORIF) of distal radius fractures. "
3.	eldecalcitol (ED 71)IBA 12/01/2012 - "Eldecalcitol also decreases wrist fractures. " 10/01/2011 - "Eldecalcitol reduced the incidence of three major non-vertebral fractures, which was due to a marked reduction in wrist fractures by a post-hoc analysis (1.1 vs. 3.6%; hazard ratio, 0.29; 95% CI, 0.11-0.77). " 01/01/2022 - "Eldecalcitol alone or a bone resorption inhibitor with eldecalcitol improved bone mass and bone mineral density, and maintained skeletal muscle mass index, muscle strength, and exercise capacity of osteoporotic patients with distal radius fractures." 01/01/2022 - "This study aimed to determine the effects of eldecalcitol alone or a bone resorption inhibitor with eldecalcitol on bone mass, limb muscle mass, and exercise capacity of osteoporotic patients with distal radius fractures and to identify the preventive effects against future fractures. " 01/01/2022 - "Effects of eldecalcitol alone or a bone resorption inhibitor with eldecalcitol on bone mineral density, muscle mass, and exercise capacity for postmenopausal women with distal radius fractures."
4.	Anesthetics (Anesthetic Agents)IBA 09/01/2012 - "To compare the efficacy of anesthetic type on clinical outcomes after operative treatment of distal radius fractures. " 11/01/2018 - "Using the WALANT approach as an alternative anesthetic for plating of distal radius fractures may enable patients who are normally denied surgery owing to their age or medical comorbidities to undergo plate fixation for the fractures. " 10/01/2018 - "Conclusion The WALANT technique offers a simple and safe alternative to traditional anesthetic techniques for open reduction and plating of distal radius fractures." 10/01/2022 - "We compare periosteal block and intravenous regional anesthesia (IVRA) as anesthetic techniques for reduction of distal radius fractures when performed by emergency department (ED) clinicians following brief training. " 12/01/2021 - "Sterile silicone ring tourniquet application is a simple, safe and effective analgesic and anesthetic technique for the operative treatment of distal radius fractures."
5.	EnzymesIBA 01/01/2009 - "The best evidence suggests that efficacy of MLDT in sports medicine and rehabilitation is specific to resolution of enzyme serum levels associated with acute skeletal muscle cell damage as well as reduction of edema following acute ankle joint sprain and radial wrist fracture. " 01/01/2005 - "The frequency of the genotype C/C(-13910) associated with adult-type hypolactasia (low lactase enzyme activity or primary lactose malabsorption (LM)) was significantly greater in individuals with hip fractures, with an adjusted odds ratio (OR) of 3.7 (95% confidence interval (CI)=1.8-7.8), wrist fractures with an adjusted OR of 2.5 (95% CI=1.2-5.2), and hip and wrist fractures combined with an adjusted OR of 4.1 (95% CI=2.0-8.3). "
6.	Vitamin D FDA LinkGeneric 01/01/2022 - "Conclusion No significant association was noted between patients with and without distal radius fracture and vitamin D levels, however, we recommend more studies on this topic so that more comprehensive results can be obtained." 01/01/2017 - "The main purpose of this study was to determine the relationship between serum vitamin D and the status of bone mineral density in patients with low-energy hip and distal radius fracture. " 03/01/2013 - "This study demonstrated that in women with a distal radius fracture, baseline vitamin D level is not associated with grip strength recovery in the injured hand. " 03/01/2013 - "The purpose of this study was to determine whether the level of vitamin D is associated with grip strength recovery in women after a distal radius fracture. " 01/01/2022 - "No significant association between distal radius fracture and vitamin D levels was found in males, whereas a significantly higher proportion of females with no fracture had a mild-moderate deficiency in comparison to females with fracture. "
7.	SugarsIBA 11/01/2004 - "The purpose of this study was to evaluate the radiographic outcome of unstable distal radius fractures treated by closed reduction and sugar tong splinting and to quantitatively evaluate Lafontaines' criteria of instability. " 04/01/2019 - "Sugar-tong splinting has been shown to maintain acceptable reduction in pediatric distal radius fractures while potentially avoiding issues associated with circumferential casting. " 01/01/2015 - "Outcomes of long-arm casting versus double-sugar-tong splinting of acute pediatric distal forearm fractures." 05/01/2010 - "Our primary objective was to determine the effectiveness of 3 immobilization methods (circumferential casting [CC], volar-dorsal splinting [VDS] and modified sugar-tong [MST] splinting) in maintaining the position of displaced distal radius fractures after successful closed reduction. " 02/01/2007 - "The sugar-tong splint is effective in maintaining reductions in pediatric distal radius fractures and has none of the added risks associated with current alternative methods."
8.	Stainless Steel (Steel, Stainless)IBA 03/01/2006 - "The treatment of distal radius fractures with a low-profile stainless steel dorsal plating system is a safe and effective method that provides stable internal fixation and allows for full extensor tendon glide and full metacarpophalangeal joint motion. " 10/01/2010 - "The use of HA-coated pins compared with standard stainless-steel pins in external fixation for unstable wrist fractures yields only a trend towards a superior clinical outcome." 12/01/2016 - "Titanium versus Stainless-Steel Plating in the Surgical Treatment of Distal Radius Fractures: A Randomized Trial." 03/11/2014 - "This study will specifically investigate and compare the clinical and radiological outcomes and complication rates of two commonly used volar plating systems for fixation of distal radius fractures: one made from stainless steel (Trimed™ Volar Plate, Trimed™, California, USA) and the other made from titanium (Medartis® Aptus Volar Plate, Medartis®, Basel, Switzerland). " 03/01/2010 - "In this study, we compared the use of a titanium 2.4-mm precontoured plate with that of a stainless-steel oblique 3.5-mm T-shaped plate to test the null hypothesis that there would be no difference in wrist function or upper extremity-specific health status in the internal fixation of AO-type A3.2 distal radius fractures. "
9.	Diphosphonates (Bisphosphonates)IBA 11/01/2017 - "Routine treatment of all women over 65 suffering distal radius fracture with bisphosphonates would result in a significant reduction in the overall hip fracture burden, however at a substantial cost of over a $2 billion dollars annually. " 12/01/2021 - "Clinical studies performed in predominantly hip and distal radius fracture patients showed no effect of bisphosphonates on fracture healing. " 09/01/2018 - "Comparative adherence to weekly oral and quarterly intravenous bisphosphonates among patients with limited heath literacy who sustained distal radius fractures." 01/01/2018 - "The Effect of Bisphosphonates on the Clinical and Radiographic Outcomes of Distal Radius Fractures in Women." 11/01/2017 - "Age specific distal radius fracture incidence, age specific hip fracture rates after distal radius fracture with and without risendronate treatment, cost of risendronate treatment, risk of atypical femur fracture with bisphosphonate treatment, and cost of hip fracture treatment were obtained from the literature. "
10.	Analgesics (Analgesic Drugs)IBA 05/01/2023 - "This study aims to compare the analgesic properties of a BB with those of an HB when manipulating distal radius fractures. " 08/01/2019 - "Materials and Methods Thirty dorsally displaced distal radius fractures were reduced and casted under finger-trap traction with intravenous analgesics. " 04/01/2019 - "To investigate whether a conventional fracture hematoma block (FHB) or an ultrasound-guided peripheral nerve block has more superior analgesic effect during nonoperative management of distal radius fractures in an emergency department setting. " 09/01/2012 - "A case is presented of a 69 year old male patient with a history of wrist fracture from over 50 years ago with pain refractory to analgesics and with joint destruction of the wrist in conventional radiology. " 01/01/2015 - "To investigate the analgesic effect of nasal salmon calcitonin on the post-fracture period of distal radius fracture. "

Therapies and Procedures

1.	Conservative Treatment 01/01/2022 - "The aim of this study was to determine whether surgical treatment is more effective than conservative treatment in terms of functional outcomes in elderly patients with distal radius fractures (DRFs). " 02/01/2013 - "Conservative management has been the mainstay of treatment for simple extra-articular distal radius fractures. " 09/01/2018 - "This study indicates that a home exercise program after conservative treatment of distal radius fracture is a safe and effective option to prevent CRPS-1. " 01/01/2019 - "The aim of this study was to evaluate the efficacy of conservative treatment (cast immobilization) for complex intra-articular distal radius fractures (AO type C) in elderly patients and to determine whether or not the application of a volar locking plate (VLP) is necessary. " 09/01/2023 - "We performed a systematic review and meta-analysis to compare the efficacy of volar locking plating (VLP) to conservative treatment in distal radius fractures in patients aged >60 years old. "
2.	Therapeutics 01/01/2022 - "This study aimed to evaluate the efficacy of hand therapy after volar locking plate fixation of distal radius fractures in middle-aged to elderly women. " 01/01/2022 - "Hand therapy improved the outcomes after volar locking plate fixation for distal radius fracture in middle-aged to elderly women at 8 weeks after surgery. " 01/01/2022 - "Efficacy of Hand Therapy After Volar Locking Plate Fixation of Distal Radius Fracture in Middle-Aged to Elderly Women: A Randomized Controlled Trial." 01/16/2020 - "A study protocol for a randomized controlled trial evaluating vibration therapy as an intervention for postural training and fall prevention after distal radius fracture in elderly patients." 10/01/2018 - "This study aims to analyze which of 5 common sequelae of the distal radius fracture is most significant for increasing the number of therapy visits. "
3.	Bone Wires 09/09/2023 - "ue to the lack of consensus on the optimal surgical treatment for distal radius fractures (DRF) in elderly patients over 65 years old, the purpose of this study was to compare the efficacy of external fixation (EF) with Kirschner wires and volar locking plate (VLP) in the treatment of DRF through a retrospective cohort study. " 05/01/2010 - "In 1913 Lambotte began treating distal radius fractures surgically using percutaneous fixation with a Kirschner wire; in 1984 Clancey modified the percutaneous technique by using crossed wires with good results; however, various therapeutic approaches are needed to treat the fractures in elderly or osteopenic patients. " 08/01/2009 - "A prospective study was conducted to evaluate the efficacy of percutaneous Kirschner-wire fixation for the management of high-risk distal forearm fractures in children. " 06/01/2013 - "This manuscript describes and evaluates the safety and efficacy of a modified Kapandji technique with insertion of a volar Kirschner wire for osteosynthesis of intra-articular distal radius fractures with a volar fragment. " 08/19/2020 - "We performed cross-sectional data analysis to compare the results of three treatments methods - volar locking plate (VLP), external fixation (EF), Kirschner wire (K-wire) - in patients with distal radius fractures, and compared the clinical, functional, and radiological results Materials and methods Forty-four patients with distal radius fractures who underwent fixation with VLP, K-wire or EF between 2011 and 2013 were included in the study. "
4.	External Fixators 10/01/2010 - "Dynamic and static external fixators both achieve good outcomes for patients with unstable distal radius fractures with comparable complication rates. " 03/30/2021 - "The purpose of this meta-analysis is to evaluate the efficacy of plate or external fixator treatments in distal radius fractures, based not only on clinical and radiographic parameters but on Health Related Quality of Life (HRQOL) parameters. " 08/01/2022 - "The aim of this study was to compare the clinical and isokinetic evaluation of distal radius fractures treated by volar locking plate (VLP) and external fixator. " 08/01/2022 - "Volar-locking plate versus external fixator in the management of distal radius fractures: An isokinetic study." 11/01/2021 - "A Prospective Observational Clinical and Radiological Study of a Modular Bridging External Fixator for Unstable Distal Radius Fractures."
5.	Splints (Splint) 02/01/2008 - "To treat the comminute distal radius fractures by improved splint, and obersve the curative effect and compare the radiology with the traditional splint. " 02/01/2008 - "The outcome of improved splint was better than that of traditional splint on the function and radiology for treating the comminute distal radius fracture." 12/20/2021 - "This study evaluates whether a circumferential cast compared to a plaster splint leads to less fracture redisplacement in reduced extra-articular distal radius fractures (DRFs). " 02/01/2020 - "The effectiveness and safety of plaster splint and splints for distal radius fractures: A systematic review and meta-analysis of randomized controlled trials." 08/01/2013 - "This study reviews a series of patients with stable distal radius fractures who have been treated with thermoplastic splint. "